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- W2064072548 abstract "In children, pneumococcus became the predominant infectious agent, after the routine use of the Hib conjugate vaccine dramatically decreased Haemophilus Influenzae type b prevalence. The incidence of invasive pneumococcal infections (IPI) and of non-invasive infections due to vaccine serotypes (VS) decreased by 80% in Europe along with a 30-40% decrease in the global incidence of IPI in this age group, after the implementation of Prevenar 7(®) routine immunization in children below 2 years of age. The decrease of IPI due to VS in other age groups was an indirect benefit. The moderate increase of non-vaccinal serotype IPI incidence did not impede the benefit of the overall program. Serotype 19A was the most frequent and carried resistance to antibiotics. Prevenar 13(®), a second-generation vaccine with six new serotypes, replaced Prevenar 7(®) in most countries after 2010, with available evidence of its effectiveness (United Kingdom, US, France)." @default.
- W2064072548 created "2016-06-24" @default.
- W2064072548 creator A5006399379 @default.
- W2064072548 date "2013-08-01" @default.
- W2064072548 modified "2023-10-16" @default.
- W2064072548 title "Ten years of experience with the pneumococcal conjugate 7-valent vaccine in children" @default.
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- W2064072548 doi "https://doi.org/10.1016/j.medmal.2013.04.006" @default.
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