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• W2064139743 abstract "Dynamic kinetic asymmetric transformation (DYKAT) of a series of 1,4-diols is carried out with Candida antarctica lipase B (CALB), Pseudomonas cepacia lipase II (PS-C II), and a ruthenium catalyst. A β-chloro-substituted 1,4-diol is successfully transformed into an optically pure 1,4-diacetate, which is a highly useful synthetic intermediate. The usefulness of the optically pure 1,4-diacetates is demonstrated by the synthesis of enantiopure 2,5-disubstituted pyrrolidines." @default.
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• W2064139743 date "2009-07-01" @default.
• W2064139743 modified "2023-10-13" @default.
• W2064139743 title "Dynamic kinetic asymmetric transformation of 1,4-diols and the preparation of trans-2,5-disubstituted pyrrolidines" @default.
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• W2064139743 doi "https://doi.org/10.1016/j.tetlet.2009.02.079" @default.
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