FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2064155570> ?p ?o ?g. }

• W2064155570 endingPage "364" @default.
• W2064155570 startingPage "357" @default.
• W2064155570 abstract "The release of neurotransmitter from presynaptic terminals depends on an increase in the intracellular Ca2+ concentration ([Ca2+]i). In addition to the opening of presynaptic Ca2+ channels during excitation, other Ca2+ transport systems may be involved in changes in [Ca2+]i. We have studied the regulation of [Ca2+]i in nerve terminals of hippocampal cells in culture by the Na(+)-Ca2+ exchanger and by mitochondria. In addition, we have measured changes in the frequency of spontaneous excitatory postsynaptic currents (sEPSC) before and after the inhibition of the exchanger and of mitochondrial metabolism. We found rather heterogeneous [Ca2+]i responses of individual presynaptic terminals after inhibition of Na(+)-Ca2+ exchange. The increase in [Ca2+]i became more uniform and much larger after additional treatment of the cells with mitochondrial inhibitors. Correspondingly, sEPSC frequencies changed very little when only Na(+)-Ca2+ exchange was inhibited, but increased dramatically after additional inhibition of mitochondria. Our results provide evidence for prominent roles of Na(+)-Ca2+ exchange and mitochondria in presynaptic Ca2+ regulation and spontaneous glutamate release." @default.
• W2064155570 created "2016-06-24" @default.
• W2064155570 creator A5023014445 @default.
• W2064155570 creator A5053819689 @default.
• W2064155570 creator A5084404570 @default.
• W2064155570 date "1999-02-28" @default.
• W2064155570 modified "2023-10-18" @default.
• W2064155570 title "Roles of Na ⁺ –Ca ²⁺ exchange and of mitochondria in the regulation of presynaptic Ca ²⁺ and spontaneous glutamate release" @default.
• W2064155570 cites W1484348587 @default.
• W2064155570 cites W1648000881 @default.
• W2064155570 cites W1938878737 @default.
• W2064155570 cites W1968505278 @default.
• W2064155570 cites W1972925133 @default.
• W2064155570 cites W1991086213 @default.
• W2064155570 cites W1992169439 @default.
• W2064155570 cites W2010465386 @default.
• W2064155570 cites W2020420593 @default.
• W2064155570 cites W2028023732 @default.
• W2064155570 cites W2028262087 @default.
• W2064155570 cites W2030781430 @default.
• W2064155570 cites W2031810599 @default.
• W2064155570 cites W2032781637 @default.
• W2064155570 cites W2033936610 @default.
• W2064155570 cites W2034780161 @default.
• W2064155570 cites W2035058927 @default.
• W2064155570 cites W2052405761 @default.
• W2064155570 cites W2058307574 @default.
• W2064155570 cites W2063817664 @default.
• W2064155570 cites W2065572905 @default.
• W2064155570 cites W2065967745 @default.
• W2064155570 cites W2067616314 @default.
• W2064155570 cites W2080728750 @default.
• W2064155570 cites W2086101155 @default.
• W2064155570 cites W2086135954 @default.
• W2064155570 cites W2094796288 @default.
• W2064155570 cites W2094821743 @default.
• W2064155570 cites W2103670573 @default.
• W2064155570 cites W2109794592 @default.
• W2064155570 cites W2124486024 @default.
• W2064155570 cites W2176061808 @default.
• W2064155570 cites W2176833444 @default.
• W2064155570 cites W2253928272 @default.
• W2064155570 cites W4238605098 @default.
• W2064155570 cites W4244723717 @default.
• W2064155570 doi "https://doi.org/10.1098/rstb.1999.0387" @default.
• W2064155570 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1692498" @default.
• W2064155570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10212484" @default.
• W2064155570 hasPublicationYear "1999" @default.
• W2064155570 type Work @default.
• W2064155570 sameAs 2064155570 @default.
• W2064155570 citedByCount "40" @default.
• W2064155570 countsByYear W20641555702012 @default.
• W2064155570 countsByYear W20641555702013 @default.
• W2064155570 countsByYear W20641555702016 @default.
• W2064155570 countsByYear W20641555702017 @default.
• W2064155570 countsByYear W20641555702018 @default.
• W2064155570 countsByYear W20641555702021 @default.
• W2064155570 crossrefType "journal-article" @default.
• W2064155570 hasAuthorship W2064155570A5023014445 @default.
• W2064155570 hasAuthorship W2064155570A5053819689 @default.
• W2064155570 hasAuthorship W2064155570A5084404570 @default.
• W2064155570 hasBestOaLocation W20641555702 @default.
• W2064155570 hasConcept C112592302 @default.
• W2064155570 hasConcept C12554922 @default.
• W2064155570 hasConcept C170493617 @default.
• W2064155570 hasConcept C185592680 @default.
• W2064155570 hasConcept C2776219046 @default.
• W2064155570 hasConcept C28859421 @default.
• W2064155570 hasConcept C55493867 @default.
• W2064155570 hasConcept C61174792 @default.
• W2064155570 hasConcept C79879829 @default.
• W2064155570 hasConcept C86803240 @default.
• W2064155570 hasConceptScore W2064155570C112592302 @default.
• W2064155570 hasConceptScore W2064155570C12554922 @default.
• W2064155570 hasConceptScore W2064155570C170493617 @default.
• W2064155570 hasConceptScore W2064155570C185592680 @default.
• W2064155570 hasConceptScore W2064155570C2776219046 @default.
• W2064155570 hasConceptScore W2064155570C28859421 @default.
• W2064155570 hasConceptScore W2064155570C55493867 @default.
• W2064155570 hasConceptScore W2064155570C61174792 @default.
• W2064155570 hasConceptScore W2064155570C79879829 @default.
• W2064155570 hasConceptScore W2064155570C86803240 @default.
• W2064155570 hasIssue "1381" @default.
• W2064155570 hasLocation W20641555701 @default.
• W2064155570 hasLocation W20641555702 @default.
• W2064155570 hasLocation W20641555703 @default.
• W2064155570 hasLocation W20641555704 @default.
• W2064155570 hasOpenAccess W2064155570 @default.
• W2064155570 hasPrimaryLocation W20641555701 @default.
• W2064155570 hasRelatedWork W1976538478 @default.
• W2064155570 hasRelatedWork W1996791699 @default.
• W2064155570 hasRelatedWork W2020393851 @default.
• W2064155570 hasRelatedWork W2073577336 @default.
• W2064155570 hasRelatedWork W2090695476 @default.
• W2064155570 hasRelatedWork W2160843619 @default.
• W2064155570 hasRelatedWork W2169900903 @default.
• W2064155570 hasRelatedWork W2247608782 @default.
• W2064155570 hasRelatedWork W2375083924 @default.

• next