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- W2064177851 abstract "Gastrointestinal (GI) nematodes are incredibly successful parasites. Choosing to live in an exposed extracellular niche, in confrontation with a potentially hostile environment, their persistent, chronic lifestyle is persuasive evidence in itself for their profound ability to modulate their hosts' immune response. Modulation is essential to avoid their own destruction but also subtly balanced to avoid compromising host survival. This review describes the early circumstantial evidence that gave clues to the immunomodulatory capabilities of the GI nematodes, the roles that T regulatory cells and alternatively activated macrophages play in this immunomodulation and provides examples of the types of specific parasite-derived factors that are known to modulate host immunity, potentiating parasite survival." @default.
- W2064177851 created "2016-06-24" @default.
- W2064177851 creator A5001122976 @default.
- W2064177851 date "2005-09-20" @default.
- W2064177851 modified "2023-09-25" @default.
- W2064177851 title "Have gastrointestinal nematodes outwitted the immune system?" @default.
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- W2064177851 doi "https://doi.org/10.1111/j.1365-3024.2005.00788.x" @default.
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