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- W2064204746 abstract "For 11 consecutive days, naive male Wistar rats were given the opportunity to acquire an operant response for infusions of acetaldehyde or Ringer's vehicle into the cerebral ventricles. The experimental group showed significantly higher rates of lever pressing than the control animals. Following the intraventricular self-administration period, all the animals in the acetaldehyde group were exposed to a free-choice between increasing concentrations of ethanol and water. The consumption of ethanol in the range of concentrations of 9 to 21% (v/v) was directly correlated to the previously established rates of self-administration of acetaldehyde. The results suggest that the central mechanisms mediating the reinforcing effects of acetaldehyde also subserve the pharmacologically reinforcing properties of ingested ethanol." @default.
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- W2064204746 date "1980-02-01" @default.
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- W2064204746 title "Intraventricular self-administration of acetaldehyde and voluntary consumption of ethanol in rats" @default.
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- W2064204746 doi "https://doi.org/10.1016/s0163-1047(80)91487-9" @default.
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