FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2064230636> ?p ?o ?g. }

• W2064230636 endingPage "438" @default.
• W2064230636 startingPage "432" @default.
• W2064230636 abstract "Bone architecture and mineralization are generally considered to be important components of bone quality, and determine bone strength in conjunction with bone mineral density. Although the features of bone quality have recently been studied under conditions in which bone density decreases, such as osteoporosis, little is known in osteosclerotic diseases. In this study, we compared the trabecular bone microarchitecture and degree of mineralization between osteoblastic bone metastasis and degenerative osteosclerosis using synchrotron radiation microcomputed tomography (SR-μCT). Small cubes of lumbar vertebrae were excised postmortem from the sites of osteoblastic metastasis, degenerative osteosclerosis, and comparative sites of normal subjects without skeletal lesions. The samples were imaged at high spatial resolution (voxel size = 6 μm) using the SR-μCT system developed at the synchrotron facility (SPring-8), Hyogo, Japan. The three-dimensional (3D) image data were then analyzed for the morphological parameters and the degree of mineralization of bone (DMB). Trabecular bone in metastatic lesions showed a highly connected and isotropic network pattern compared with the normal samples. Although the trabecular surface was markedly irregular in osteoblastic metastases, no significant difference was found in the mean trabecular thickness (Tb.Th) between osteoblastic metastases and normal tissue. The DMB of trabeculae in metastatic lesions had a broader range and lower mean than that of the normal tissue. In contrast, trabecular bone in degenerative osteosclerotic lesions showed a similar degree of anisotropy (DA) and connectivity to the normal tissue, whereas the trabecular thickness was greater in the degenerative osteosclerotic lesions. No significant difference in DBM between degenerative osteosclerosis and normal tissue was detected. These results characterize the difference in bone quality between osteoblastic bone metastasis and degenerative osteosclerosis. Further study on the relationship between bone quality and bone strength in these osteosclerotic lesions would improve our understanding of the pathogenesis of bone fragility." @default.
• W2064230636 created "2016-06-24" @default.
• W2064230636 creator A5012809776 @default.
• W2064230636 creator A5031011136 @default.
• W2064230636 creator A5032820934 @default.
• W2064230636 creator A5033458686 @default.
• W2064230636 creator A5053562519 @default.
• W2064230636 date "2004-08-01" @default.
• W2064230636 modified "2023-10-02" @default.
• W2064230636 title "Analysis of three-dimensional microarchitecture and degree of mineralization in bone metastases from prostate cancer using synchrotron microcomputed tomography" @default.
• W2064230636 cites W1539952988 @default.
• W2064230636 cites W175660244 @default.
• W2064230636 cites W1964983194 @default.
• W2064230636 cites W1974395735 @default.
• W2064230636 cites W1989783674 @default.
• W2064230636 cites W1996767999 @default.
• W2064230636 cites W2000175914 @default.
• W2064230636 cites W2001544310 @default.
• W2064230636 cites W2003508313 @default.
• W2064230636 cites W2012961078 @default.
• W2064230636 cites W2013583479 @default.
• W2064230636 cites W2018930422 @default.
• W2064230636 cites W2019724281 @default.
• W2064230636 cites W2025081386 @default.
• W2064230636 cites W2032244293 @default.
• W2064230636 cites W2033933902 @default.
• W2064230636 cites W2047022551 @default.
• W2064230636 cites W2068224700 @default.
• W2064230636 cites W2068707779 @default.
• W2064230636 cites W2075817269 @default.
• W2064230636 cites W2086556166 @default.
• W2064230636 cites W2087378917 @default.
• W2064230636 cites W2088392474 @default.
• W2064230636 cites W2092527161 @default.
• W2064230636 cites W2092640758 @default.
• W2064230636 cites W2093871127 @default.
• W2064230636 cites W2094977068 @default.
• W2064230636 cites W2105002035 @default.
• W2064230636 cites W2133209217 @default.
• W2064230636 cites W2149598802 @default.
• W2064230636 cites W2498788895 @default.
• W2064230636 cites W4233857083 @default.
• W2064230636 cites W4237771509 @default.
• W2064230636 cites W4301464234 @default.
• W2064230636 doi "https://doi.org/10.1016/j.bone.2004.05.011" @default.
• W2064230636 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15268894" @default.
• W2064230636 hasPublicationYear "2004" @default.
• W2064230636 type Work @default.
• W2064230636 sameAs 2064230636 @default.
• W2064230636 citedByCount "66" @default.
• W2064230636 countsByYear W20642306362012 @default.
• W2064230636 countsByYear W20642306362013 @default.
• W2064230636 countsByYear W20642306362014 @default.
• W2064230636 countsByYear W20642306362015 @default.
• W2064230636 countsByYear W20642306362016 @default.
• W2064230636 countsByYear W20642306362017 @default.
• W2064230636 countsByYear W20642306362018 @default.
• W2064230636 countsByYear W20642306362019 @default.
• W2064230636 countsByYear W20642306362020 @default.
• W2064230636 countsByYear W20642306362022 @default.
• W2064230636 countsByYear W20642306362023 @default.
• W2064230636 crossrefType "journal-article" @default.
• W2064230636 hasAuthorship W2064230636A5012809776 @default.
• W2064230636 hasAuthorship W2064230636A5031011136 @default.
• W2064230636 hasAuthorship W2064230636A5032820934 @default.
• W2064230636 hasAuthorship W2064230636A5033458686 @default.
• W2064230636 hasAuthorship W2064230636A5053562519 @default.
• W2064230636 hasConcept C105702510 @default.
• W2064230636 hasConcept C121608353 @default.
• W2064230636 hasConcept C126322002 @default.
• W2064230636 hasConcept C142724271 @default.
• W2064230636 hasConcept C2776541429 @default.
• W2064230636 hasConcept C2777479973 @default.
• W2064230636 hasConcept C2777783956 @default.
• W2064230636 hasConcept C2780192828 @default.
• W2064230636 hasConcept C2989005 @default.
• W2064230636 hasConcept C71924100 @default.
• W2064230636 hasConceptScore W2064230636C105702510 @default.
• W2064230636 hasConceptScore W2064230636C121608353 @default.
• W2064230636 hasConceptScore W2064230636C126322002 @default.
• W2064230636 hasConceptScore W2064230636C142724271 @default.
• W2064230636 hasConceptScore W2064230636C2776541429 @default.
• W2064230636 hasConceptScore W2064230636C2777479973 @default.
• W2064230636 hasConceptScore W2064230636C2777783956 @default.
• W2064230636 hasConceptScore W2064230636C2780192828 @default.
• W2064230636 hasConceptScore W2064230636C2989005 @default.
• W2064230636 hasConceptScore W2064230636C71924100 @default.
• W2064230636 hasIssue "2" @default.
• W2064230636 hasLocation W20642306361 @default.
• W2064230636 hasLocation W20642306362 @default.
• W2064230636 hasOpenAccess W2064230636 @default.
• W2064230636 hasPrimaryLocation W20642306361 @default.
• W2064230636 hasRelatedWork W1994769697 @default.
• W2064230636 hasRelatedWork W2045006939 @default.
• W2064230636 hasRelatedWork W2171470317 @default.
• W2064230636 hasRelatedWork W2358157500 @default.
• W2064230636 hasRelatedWork W2375435548 @default.
• W2064230636 hasRelatedWork W2392688306 @default.

• next