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• W2064258387 abstract "Key steps in regulating actin dynamics are the de novo nucleation and elongation of actin filaments, which can be catalysed by a limited number of proteins and protein complexes. Among these, Arp2/3 complex and formins are the best studied. Arp2/3-complex activity is controlled through signalling-dependent association with nucleation-promoting factors, such as the WASP/WAVE family proteins. A common theme for these molecules, which is well established for WAVEs but is only just beginning to emerge for WASPs, is that they act as coincident detectors of a variety of signalling pathways through the formation of large multi-molecular complexes." @default.
• W2064258387 created "2016-06-24" @default.
• W2064258387 creator A5036132330 @default.
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• W2064258387 date "2006-02-01" @default.
• W2064258387 modified "2023-10-18" @default.
• W2064258387 title "Protein complexes regulating Arp2/3-mediated actin assembly" @default.
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• W2064258387 doi "https://doi.org/10.1016/j.ceb.2005.12.003" @default.
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