FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2064292506> ?p ?o ?g. }

• W2064292506 endingPage "360" @default.
• W2064292506 startingPage "351" @default.
• W2064292506 abstract "Background. Tea from the Camellia sinensis species of the Theaceae family is one of the most ancient and, next to water, the most widely consumed beverage in the world. Since tea contains several polyphenols and since several other naturally occurring dietary polyphenols have shown antimutagenic effects in bacteria and anticarcinogenic effects in animal bioassay systems, we studied whether polyphenols extracted from Chinese green tea (GTP) also possess antimutagenic and anticarcinogenic effects. Results. GTP and its constituent epicatechin derivatives were found to interact with hepatic cytochrome P450 (P450) and inhibited the P450-dependent mixed-function oxidase enzymes in skin and liver. GTP and its epicatechin derivatives exhibited antimutagenic effects in several test systems. GTP showed substantial anti-skin-tumor-initiating and anti-skin-tumor-promoting activities when assessed in murine skin tumorigenesis bioassay systems. In these model systems polyaromatic hydrocarbons, benzo[a]pyrene (BP), 3-methyl-cholanthrene, 7,12-dimethylbenz[a]anthracene, and (+)-7β,8α-dihydroxy-9α,10α-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (an ultimate carcinogenic metabolite of BP) were used as model skin carcinogens. The feeding of GTP in drinking water to SKH-1 hairless mice also afforded significant protection against ultraviolet-B-radiation-induced skin photocarcinogenesis. Conclusions. These data suggest that tea components possess antimutagenic and anti-carcinogenic effects, and that they could protect humans against the risk of cancer by environmental agents." @default.
• W2064292506 created "2016-06-24" @default.
• W2064292506 creator A5036743590 @default.
• W2064292506 creator A5048444823 @default.
• W2064292506 creator A5082425428 @default.
• W2064292506 creator A5087222455 @default.
• W2064292506 date "1992-05-01" @default.
• W2064292506 modified "2023-09-23" @default.
• W2064292506 title "Tea components: Antimutagenic and anticarcinogenic effects" @default.
• W2064292506 cites W1525750060 @default.
• W2064292506 cites W1972002448 @default.
• W2064292506 cites W1973321618 @default.
• W2064292506 cites W1977908472 @default.
• W2064292506 cites W1981444353 @default.
• W2064292506 cites W1992108302 @default.
• W2064292506 cites W2002935797 @default.
• W2064292506 cites W2026398700 @default.
• W2064292506 cites W2049581949 @default.
• W2064292506 cites W2074605208 @default.
• W2064292506 cites W2318608535 @default.
• W2064292506 cites W2614442853 @default.
• W2064292506 cites W95569404 @default.
• W2064292506 doi "https://doi.org/10.1016/0091-7435(92)90042-g" @default.
• W2064292506 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1614996" @default.
• W2064292506 hasPublicationYear "1992" @default.
• W2064292506 type Work @default.
• W2064292506 sameAs 2064292506 @default.
• W2064292506 citedByCount "145" @default.
• W2064292506 countsByYear W20642925062012 @default.
• W2064292506 countsByYear W20642925062013 @default.
• W2064292506 countsByYear W20642925062014 @default.
• W2064292506 countsByYear W20642925062015 @default.
• W2064292506 countsByYear W20642925062016 @default.
• W2064292506 countsByYear W20642925062017 @default.
• W2064292506 countsByYear W20642925062018 @default.
• W2064292506 countsByYear W20642925062019 @default.
• W2064292506 countsByYear W20642925062020 @default.
• W2064292506 countsByYear W20642925062021 @default.
• W2064292506 countsByYear W20642925062022 @default.
• W2064292506 crossrefType "journal-article" @default.
• W2064292506 hasAuthorship W2064292506A5036743590 @default.
• W2064292506 hasAuthorship W2064292506A5048444823 @default.
• W2064292506 hasAuthorship W2064292506A5082425428 @default.
• W2064292506 hasAuthorship W2064292506A5087222455 @default.
• W2064292506 hasConcept C104317684 @default.
• W2064292506 hasConcept C104488531 @default.
• W2064292506 hasConcept C114246631 @default.
• W2064292506 hasConcept C118716 @default.
• W2064292506 hasConcept C181199279 @default.
• W2064292506 hasConcept C185592680 @default.
• W2064292506 hasConcept C2777477808 @default.
• W2064292506 hasConcept C2778004101 @default.
• W2064292506 hasConcept C2779156968 @default.
• W2064292506 hasConcept C2992816389 @default.
• W2064292506 hasConcept C31903555 @default.
• W2064292506 hasConcept C33070731 @default.
• W2064292506 hasConcept C54355233 @default.
• W2064292506 hasConcept C55493867 @default.
• W2064292506 hasConcept C555283112 @default.
• W2064292506 hasConcept C59822182 @default.
• W2064292506 hasConcept C70899900 @default.
• W2064292506 hasConcept C71924100 @default.
• W2064292506 hasConcept C86803240 @default.
• W2064292506 hasConcept C98274493 @default.
• W2064292506 hasConceptScore W2064292506C104317684 @default.
• W2064292506 hasConceptScore W2064292506C104488531 @default.
• W2064292506 hasConceptScore W2064292506C114246631 @default.
• W2064292506 hasConceptScore W2064292506C118716 @default.
• W2064292506 hasConceptScore W2064292506C181199279 @default.
• W2064292506 hasConceptScore W2064292506C185592680 @default.
• W2064292506 hasConceptScore W2064292506C2777477808 @default.
• W2064292506 hasConceptScore W2064292506C2778004101 @default.
• W2064292506 hasConceptScore W2064292506C2779156968 @default.
• W2064292506 hasConceptScore W2064292506C2992816389 @default.
• W2064292506 hasConceptScore W2064292506C31903555 @default.
• W2064292506 hasConceptScore W2064292506C33070731 @default.
• W2064292506 hasConceptScore W2064292506C54355233 @default.
• W2064292506 hasConceptScore W2064292506C55493867 @default.
• W2064292506 hasConceptScore W2064292506C555283112 @default.
• W2064292506 hasConceptScore W2064292506C59822182 @default.
• W2064292506 hasConceptScore W2064292506C70899900 @default.
• W2064292506 hasConceptScore W2064292506C71924100 @default.
• W2064292506 hasConceptScore W2064292506C86803240 @default.
• W2064292506 hasConceptScore W2064292506C98274493 @default.
• W2064292506 hasIssue "3" @default.
• W2064292506 hasLocation W20642925061 @default.
• W2064292506 hasLocation W20642925062 @default.
• W2064292506 hasOpenAccess W2064292506 @default.
• W2064292506 hasPrimaryLocation W20642925061 @default.
• W2064292506 hasRelatedWork W1968931183 @default.
• W2064292506 hasRelatedWork W1979171525 @default.
• W2064292506 hasRelatedWork W2021365476 @default.
• W2064292506 hasRelatedWork W2029251984 @default.
• W2064292506 hasRelatedWork W2052217423 @default.
• W2064292506 hasRelatedWork W2057725215 @default.
• W2064292506 hasRelatedWork W2068894770 @default.
• W2064292506 hasRelatedWork W2080290402 @default.
• W2064292506 hasRelatedWork W2148253648 @default.

• next