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- W2064298312 abstract "A series of 23 quinazolines and 5,6,7,8-tetrahydroquinazolines was evaluated for inhibition of bovine milk xanthine oxidase. The synthesis of four of these compounds has not been reported previously. Several 2-amino-4-hydroxyquinazolines, as well as 2-amino-4-mercaptoquinazoline, were effective inhibitors of this enzyme. 2-Amino-4-hydroxy-6-hydroxymethylquinazoline was a threefold better inhibitor than its pteridine counterpart, while 2-amino-4-hydroxyquinazoline-6-carboxaldehyde was the most potent compound studied." @default.
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- W2064298312 date "1974-07-01" @default.
- W2064298312 modified "2023-10-14" @default.
- W2064298312 title "Quinazolines as Inhibitors of Xanthe Oxidase" @default.
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- W2064298312 doi "https://doi.org/10.1002/jps.2600630732" @default.
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