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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2064352008> ?p ?o ?g. }

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• W2064352008 abstract "We investigated whether immunization with recombinant anti-idiotypic antibody fragments mimicking the conformation of the capsular antigen can protect against infection by group B streptococcus, an important neonatal pathogen. Single-chain fragment-variable anti-idiotypes competed with the type III carbohydrate for binding to type-specific antibodies and elicited, in mice, the production of protective immunoglobulins reacting against the type III polysaccharide. Moreover, maternal immunization with soluble or phage-displayed fragments protected neonatal mice against streptococcal infection. These data indicate that recombinant anti-idiotypic antibodies may be useful in developing protein images of relevant carbohydrate epitopes and, ultimately, in preventing infections by encapsulated bacteria." @default.
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• W2064352008 date "1998-06-01" @default.
• W2064352008 modified "2023-10-01" @default.
• W2064352008 title "Neonatal mouse immunity against group B streptococcal infection by maternal vaccination with recombinant anti-idiotypes" @default.
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• W2064352008 doi "https://doi.org/10.1038/nm0698-705" @default.
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