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• W2064375802 endingPage "1217" @default.
• W2064375802 startingPage "1211" @default.
• W2064375802 abstract "A new antitumor antibiotic is produced in fermentation liquors of Streptomyces zelensis sp.n. The antibiotic is biologically active at extremely low concentrations. At 40 pg/ml, it inhibited 90% of the growth of L1210 cells in culture in tube dilution assays. The minimal inhibitory concentrations against Gram-positive bacteria is between 1 approximately 10 ng/ml, while these values for Gram-negative bacteria and fungi are mostly under 1 microgram/ml. A microbiological assay with Bacillus subtilis can detect concentrations of 1 approximately 2 ng/ml." @default.
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• W2064375802 date "1978-01-01" @default.
• W2064375802 modified "2023-10-16" @default.
• W2064375802 title "CC-1065 (NSC-298223), a new antitumor antibiotic. Production, in vitro biological activity, microbiological assays and taxonomy of the producing microorganism." @default.
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• W2064375802 doi "https://doi.org/10.7164/antibiotics.31.1211" @default.
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