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- W2064396947 abstract "Summary Four cases of myelofibrosis and myelosclerosis and four with chronic myeloid leukaemia are compared in respect of clinical features, haematological and radioisotopic (radioiron and radiochromium) investigations. The two diseases have a similar clinical presentation, but may be differentiated by blood and bone marrow investigations. The mechanism of the anaemia in these conditions is the same, namely a combination of marrow hypoplasia and increased haemolysis. The spleen may or may not be the site of extramedullary erythropoiesis in either condition; it may be the site of erythrocyte destruction. The results of the radioisotopic investigations proved helpful when splenectomy and splenic irradiation were considered in the treatment of patients with myelofibrosis." @default.
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- W2064396947 date "1960-10-01" @default.
- W2064396947 modified "2023-09-27" @default.
- W2064396947 title "The diagnosis and management of myelofibrosis, myelosclerosis and chronic myeloid leukaemia" @default.
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- W2064396947 doi "https://doi.org/10.1016/s0009-9260(60)80052-9" @default.
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