Matches in SemOpenAlex for { <https://semopenalex.org/work/W2064439912> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2064439912 endingPage "8" @default.
- W2064439912 startingPage "163" @default.
- W2064439912 abstract "Relaxin-like factor (RLF), also known as the Leydig cell insulin-like factor (Ley-I-L), is a novel member of the insulin-IGF-relaxin family of hormones and growth factors that has recently been shown to be strongly expressed in testicular Leydig cells. Expression of the RLF peptide in the human ovary and in ovarian tumors has not been studied. In the present study, the expression of the RLF peptide in the human ovary was investigated by immunohistochemistry using a specific antibody raised against human RLF. By this method, RLF was found to be expressed in hilus (Leydig) cells and theca interna cells but absent in granulosa cells, ovarian stromal cells, and surface epithelium. RLF expression was also observed in the corpus luteum, although at a lower level than in theca cells. Thirty-seven sex cord-stromal tumors and five cases of hilar Leydig cell hyperplasia were also investigated for RLF expression. RLF was found to be strongly expressed in hilar Leydig cell hyperplasia and sex cord-stromal tumors with a component of Leydig or luteinized cells. Of the analyzed theca cell tumors, two displayed a diffuse staining pattern. As expected, RLF was not expressed in granulosa cell tumors. In conclusion, RLF appears to be a useful marker for Leydig cells in the human ovary and may be a diagnostic supplement in hyperplasias and tumors derived therefrom." @default.
- W2064439912 created "2016-06-24" @default.
- W2064439912 creator A5017106218 @default.
- W2064439912 creator A5027934616 @default.
- W2064439912 creator A5032908348 @default.
- W2064439912 creator A5040377341 @default.
- W2064439912 creator A5045797580 @default.
- W2064439912 creator A5067777627 @default.
- W2064439912 creator A5086629081 @default.
- W2064439912 date "1999-04-01" @default.
- W2064439912 modified "2023-10-18" @default.
- W2064439912 title "Relaxin-like factor (RLF): a new specific marker for Leydig cells in the ovary." @default.
- W2064439912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10202675" @default.
- W2064439912 hasPublicationYear "1999" @default.
- W2064439912 type Work @default.
- W2064439912 sameAs 2064439912 @default.
- W2064439912 citedByCount "22" @default.
- W2064439912 countsByYear W20644399122012 @default.
- W2064439912 countsByYear W20644399122013 @default.
- W2064439912 countsByYear W20644399122016 @default.
- W2064439912 countsByYear W20644399122017 @default.
- W2064439912 countsByYear W20644399122019 @default.
- W2064439912 countsByYear W20644399122020 @default.
- W2064439912 countsByYear W20644399122021 @default.
- W2064439912 countsByYear W20644399122022 @default.
- W2064439912 crossrefType "journal-article" @default.
- W2064439912 hasAuthorship W2064439912A5017106218 @default.
- W2064439912 hasAuthorship W2064439912A5027934616 @default.
- W2064439912 hasAuthorship W2064439912A5032908348 @default.
- W2064439912 hasAuthorship W2064439912A5040377341 @default.
- W2064439912 hasAuthorship W2064439912A5045797580 @default.
- W2064439912 hasAuthorship W2064439912A5067777627 @default.
- W2064439912 hasAuthorship W2064439912A5086629081 @default.
- W2064439912 hasConcept C126322002 @default.
- W2064439912 hasConcept C134018914 @default.
- W2064439912 hasConcept C16685009 @default.
- W2064439912 hasConcept C16930146 @default.
- W2064439912 hasConcept C175805485 @default.
- W2064439912 hasConcept C203014093 @default.
- W2064439912 hasConcept C204232928 @default.
- W2064439912 hasConcept C2777121736 @default.
- W2064439912 hasConcept C2777203538 @default.
- W2064439912 hasConcept C2777562237 @default.
- W2064439912 hasConcept C2777736315 @default.
- W2064439912 hasConcept C2778324911 @default.
- W2064439912 hasConcept C2778575703 @default.
- W2064439912 hasConcept C2909546088 @default.
- W2064439912 hasConcept C502942594 @default.
- W2064439912 hasConcept C71315377 @default.
- W2064439912 hasConcept C71924100 @default.
- W2064439912 hasConcept C86803240 @default.
- W2064439912 hasConceptScore W2064439912C126322002 @default.
- W2064439912 hasConceptScore W2064439912C134018914 @default.
- W2064439912 hasConceptScore W2064439912C16685009 @default.
- W2064439912 hasConceptScore W2064439912C16930146 @default.
- W2064439912 hasConceptScore W2064439912C175805485 @default.
- W2064439912 hasConceptScore W2064439912C203014093 @default.
- W2064439912 hasConceptScore W2064439912C204232928 @default.
- W2064439912 hasConceptScore W2064439912C2777121736 @default.
- W2064439912 hasConceptScore W2064439912C2777203538 @default.
- W2064439912 hasConceptScore W2064439912C2777562237 @default.
- W2064439912 hasConceptScore W2064439912C2777736315 @default.
- W2064439912 hasConceptScore W2064439912C2778324911 @default.
- W2064439912 hasConceptScore W2064439912C2778575703 @default.
- W2064439912 hasConceptScore W2064439912C2909546088 @default.
- W2064439912 hasConceptScore W2064439912C502942594 @default.
- W2064439912 hasConceptScore W2064439912C71315377 @default.
- W2064439912 hasConceptScore W2064439912C71924100 @default.
- W2064439912 hasConceptScore W2064439912C86803240 @default.
- W2064439912 hasIssue "2" @default.
- W2064439912 hasLocation W20644399121 @default.
- W2064439912 hasOpenAccess W2064439912 @default.
- W2064439912 hasPrimaryLocation W20644399121 @default.
- W2064439912 hasRelatedWork W151065835 @default.
- W2064439912 hasRelatedWork W1996716247 @default.
- W2064439912 hasRelatedWork W2041908370 @default.
- W2064439912 hasRelatedWork W2048170199 @default.
- W2064439912 hasRelatedWork W2064439912 @default.
- W2064439912 hasRelatedWork W2075052643 @default.
- W2064439912 hasRelatedWork W2092889645 @default.
- W2064439912 hasRelatedWork W2128236673 @default.
- W2064439912 hasRelatedWork W2147680826 @default.
- W2064439912 hasRelatedWork W2152080735 @default.
- W2064439912 hasVolume "18" @default.
- W2064439912 isParatext "false" @default.
- W2064439912 isRetracted "false" @default.
- W2064439912 magId "2064439912" @default.
- W2064439912 workType "article" @default.