Matches in SemOpenAlex for { <https://semopenalex.org/work/W2064442953> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2064442953 endingPage "308" @default.
- W2064442953 startingPage "298" @default.
- W2064442953 abstract "Reaggregate cultures have been formed from cell suspensions of neonatal rat retinas. Histological sections of the reaggregates showed evidence of lamination with central rosettes formed around a lumen, a clear neuropil layer and an outer cellular layer. Each of the major retinal cell types, except ganglion cells, could be positively identified using cell type-specific antibodies to label cryostat sections. Many of these were found to occupy positions within the reaggregates similar to those found in the intact retina. Electron microscopic observations showed abundant immature and mature synaptic endings within the neuropil layer, including a number of ribbon synapses. Examination of the rosettes showed an arrangement of Müller glia and photoreceptors that closely resembled that of the intact retina. Within the lumen of rosettes, photoreceptors were found to contain stacks of disc-like membranes bounded by a plasma membrane, analogous to immature outer segments. The photoreceptors within rosettes also underwent molecular differentiation and expressed an outer segment specific marker. The findings suggest that retinal cells have intrinsic properties that allow them to organize themselves into a correctly laminated structure and that particular cell interactions are necessary for continued differentiation of at least rod photoreceptors and Müller cells." @default.
- W2064442953 created "2016-06-24" @default.
- W2064442953 creator A5001481519 @default.
- W2064442953 creator A5007966580 @default.
- W2064442953 creator A5039673602 @default.
- W2064442953 date "1987-12-01" @default.
- W2064442953 modified "2023-09-24" @default.
- W2064442953 title "Histiotypic organization and cell differentiation in rat retinal reaggregate cultures" @default.
- W2064442953 cites W1494751192 @default.
- W2064442953 cites W1571364237 @default.
- W2064442953 cites W1598173435 @default.
- W2064442953 cites W1762551333 @default.
- W2064442953 cites W1965166015 @default.
- W2064442953 cites W1966653793 @default.
- W2064442953 cites W1969598389 @default.
- W2064442953 cites W1970380611 @default.
- W2064442953 cites W1973336785 @default.
- W2064442953 cites W1989191938 @default.
- W2064442953 cites W1991190018 @default.
- W2064442953 cites W1991995254 @default.
- W2064442953 cites W2004567361 @default.
- W2064442953 cites W2011931446 @default.
- W2064442953 cites W2013224191 @default.
- W2064442953 cites W2026842644 @default.
- W2064442953 cites W2034249300 @default.
- W2064442953 cites W2034312760 @default.
- W2064442953 cites W2046556165 @default.
- W2064442953 cites W2049550397 @default.
- W2064442953 cites W2057378701 @default.
- W2064442953 cites W2058042895 @default.
- W2064442953 cites W2060144099 @default.
- W2064442953 cites W2064348567 @default.
- W2064442953 cites W2075228214 @default.
- W2064442953 cites W2154046995 @default.
- W2064442953 doi "https://doi.org/10.1016/0006-8993(87)91644-1" @default.
- W2064442953 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3435839" @default.
- W2064442953 hasPublicationYear "1987" @default.
- W2064442953 type Work @default.
- W2064442953 sameAs 2064442953 @default.
- W2064442953 citedByCount "50" @default.
- W2064442953 countsByYear W20644429532019 @default.
- W2064442953 crossrefType "journal-article" @default.
- W2064442953 hasAuthorship W2064442953A5001481519 @default.
- W2064442953 hasAuthorship W2064442953A5007966580 @default.
- W2064442953 hasAuthorship W2064442953A5039673602 @default.
- W2064442953 hasConcept C105702510 @default.
- W2064442953 hasConcept C12554922 @default.
- W2064442953 hasConcept C1491633281 @default.
- W2064442953 hasConcept C169760540 @default.
- W2064442953 hasConcept C189014844 @default.
- W2064442953 hasConcept C2777093970 @default.
- W2064442953 hasConcept C2777831001 @default.
- W2064442953 hasConcept C2780827179 @default.
- W2064442953 hasConcept C529278444 @default.
- W2064442953 hasConcept C55493867 @default.
- W2064442953 hasConcept C59822182 @default.
- W2064442953 hasConcept C86803240 @default.
- W2064442953 hasConcept C95444343 @default.
- W2064442953 hasConceptScore W2064442953C105702510 @default.
- W2064442953 hasConceptScore W2064442953C12554922 @default.
- W2064442953 hasConceptScore W2064442953C1491633281 @default.
- W2064442953 hasConceptScore W2064442953C169760540 @default.
- W2064442953 hasConceptScore W2064442953C189014844 @default.
- W2064442953 hasConceptScore W2064442953C2777093970 @default.
- W2064442953 hasConceptScore W2064442953C2777831001 @default.
- W2064442953 hasConceptScore W2064442953C2780827179 @default.
- W2064442953 hasConceptScore W2064442953C529278444 @default.
- W2064442953 hasConceptScore W2064442953C55493867 @default.
- W2064442953 hasConceptScore W2064442953C59822182 @default.
- W2064442953 hasConceptScore W2064442953C86803240 @default.
- W2064442953 hasConceptScore W2064442953C95444343 @default.
- W2064442953 hasIssue "2" @default.
- W2064442953 hasLocation W20644429531 @default.
- W2064442953 hasLocation W20644429532 @default.
- W2064442953 hasOpenAccess W2064442953 @default.
- W2064442953 hasPrimaryLocation W20644429531 @default.
- W2064442953 hasRelatedWork W2064442953 @default.
- W2064442953 hasRelatedWork W2065736903 @default.
- W2064442953 hasRelatedWork W2122265260 @default.
- W2064442953 hasRelatedWork W2290673031 @default.
- W2064442953 hasRelatedWork W2338171046 @default.
- W2064442953 hasRelatedWork W2402345182 @default.
- W2064442953 hasRelatedWork W2972645474 @default.
- W2064442953 hasRelatedWork W4281746817 @default.
- W2064442953 hasRelatedWork W4284990468 @default.
- W2064442953 hasRelatedWork W4290366609 @default.
- W2064442953 hasVolume "437" @default.
- W2064442953 isParatext "false" @default.
- W2064442953 isRetracted "false" @default.
- W2064442953 magId "2064442953" @default.
- W2064442953 workType "article" @default.