FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2064443311> ?p ?o ?g. }

• W2064443311 abstract "Although severe sepsis constitutes an important burden for healthcare systems, there is limited nationwide data on its epidemiology in European countries. Our objective was to examine the most recent epidemiological characteristics and trends of severe sepsis in Spain, from a population perspective. Analysis of the 2006-2011 National Hospital Discharge Registry. Cases were identified by combining specific ICD-9CM codes. We estimated demographics, clinical characteristics and outcomes and calculated age- and sex- adjusted estimations of incidence and mortality rates. Trends were assessed in terms of annual percent change (APC) in rates using joinpoint regression analysis. Over the 6-year period we identified 240939 cases of severe sepsis nationwide representing 1.1% of all hospitalisations and 54% of hospitalisations with sepsis. Incidence was 87 cases per 100,000 population. Overall 58% of cases were men, 66% were over the age of 65 and about 67% had associated comorbidities. Bacteremia was coded in 16% of records. Almost 54% of cases had one organ dysfunction, 26% two and around 20% three or more dysfunctions. In-hospital case-fatality was 43% and associated with age, gender, comorbidities and organ dysfunctions, among others. We found significant demographic and clinical changes over time with an increase in the mean age of cases, comorbidities, number of organ dysfunctions and in the number of cases with gram-negative pathogens. Furthermore, even with gender disparities, standardised incidence and mortality rates increased with an overall APC of 8.6% (95% CI 5.1, 12.1) and 6% (95% CI 1.9, 10.3), respectively. Conversely, we detect a significant decrease in case-fatality rates with an overall APC of -3.24% (95% CI: -4.2, -2.2). This nationwide population-based study shows that hospitalizations with severe sepsis are frequent and associated with substantial in-hospital mortality in Spain. Furthermore it indicates that the incidence and mortality rates of severe sepsis have notably increased in recent years, showing also a significant increase in the age and severity of the affected population. Despite this, there has been a significant decreasing trend in case-fatality rates over time. This information has significant implications for health-care system planning and may prove useful to estimate future care requirements." @default.
• W2064443311 created "2016-06-24" @default.
• W2064443311 creator A5007396300 @default.
• W2064443311 creator A5045326249 @default.
• W2064443311 creator A5053146695 @default.
• W2064443311 creator A5085687822 @default.
• W2064443311 date "2014-12-01" @default.
• W2064443311 modified "2023-10-06" @default.
• W2064443311 title "Epidemiology and recent trends of severe sepsis in Spain: a nationwide population-based analysis (2006-2011)" @default.
• W2064443311 cites W1588348816 @default.
• W2064443311 cites W1967278969 @default.
• W2064443311 cites W1971509842 @default.
• W2064443311 cites W1986836608 @default.
• W2064443311 cites W1993440563 @default.
• W2064443311 cites W1996033260 @default.
• W2064443311 cites W1999164035 @default.
• W2064443311 cites W2006558163 @default.
• W2064443311 cites W2007497300 @default.
• W2064443311 cites W2009527638 @default.
• W2064443311 cites W2019952254 @default.
• W2064443311 cites W2034261276 @default.
• W2064443311 cites W2036873150 @default.
• W2064443311 cites W2047450778 @default.
• W2064443311 cites W2049927822 @default.
• W2064443311 cites W2052426921 @default.
• W2064443311 cites W2057117982 @default.
• W2064443311 cites W2071741302 @default.
• W2064443311 cites W2073015584 @default.
• W2064443311 cites W2075164504 @default.
• W2064443311 cites W2077618811 @default.
• W2064443311 cites W2094043926 @default.
• W2064443311 cites W2095497639 @default.
• W2064443311 cites W2098572294 @default.
• W2064443311 cites W2101082552 @default.
• W2064443311 cites W2103053257 @default.
• W2064443311 cites W2117437948 @default.
• W2064443311 cites W2122844796 @default.
• W2064443311 cites W2126216107 @default.
• W2064443311 cites W2129168200 @default.
• W2064443311 cites W2129203245 @default.
• W2064443311 cites W2131535475 @default.
• W2064443311 cites W2145577370 @default.
• W2064443311 cites W2164990391 @default.
• W2064443311 cites W2167727535 @default.
• W2064443311 cites W2167950733 @default.
• W2064443311 cites W2172137144 @default.
• W2064443311 cites W2325286363 @default.
• W2064443311 cites W3022423927 @default.
• W2064443311 doi "https://doi.org/10.1186/s12879-014-0717-7" @default.
• W2064443311 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4327809" @default.
• W2064443311 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25528662" @default.
• W2064443311 hasPublicationYear "2014" @default.
• W2064443311 type Work @default.
• W2064443311 sameAs 2064443311 @default.
• W2064443311 citedByCount "73" @default.
• W2064443311 countsByYear W20644433112015 @default.
• W2064443311 countsByYear W20644433112016 @default.
• W2064443311 countsByYear W20644433112017 @default.
• W2064443311 countsByYear W20644433112018 @default.
• W2064443311 countsByYear W20644433112019 @default.
• W2064443311 countsByYear W20644433112020 @default.
• W2064443311 countsByYear W20644433112021 @default.
• W2064443311 countsByYear W20644433112022 @default.
• W2064443311 countsByYear W20644433112023 @default.
• W2064443311 crossrefType "journal-article" @default.
• W2064443311 hasAuthorship W2064443311A5007396300 @default.
• W2064443311 hasAuthorship W2064443311A5045326249 @default.
• W2064443311 hasAuthorship W2064443311A5053146695 @default.
• W2064443311 hasAuthorship W2064443311A5085687822 @default.
• W2064443311 hasBestOaLocation W20644433111 @default.
• W2064443311 hasConcept C107130276 @default.
• W2064443311 hasConcept C120665830 @default.
• W2064443311 hasConcept C121332964 @default.
• W2064443311 hasConcept C126322002 @default.
• W2064443311 hasConcept C144024400 @default.
• W2064443311 hasConcept C149923435 @default.
• W2064443311 hasConcept C187212893 @default.
• W2064443311 hasConcept C187316915 @default.
• W2064443311 hasConcept C194828623 @default.
• W2064443311 hasConcept C2778384902 @default.
• W2064443311 hasConcept C2779159551 @default.
• W2064443311 hasConcept C2779443120 @default.
• W2064443311 hasConcept C2908647359 @default.
• W2064443311 hasConcept C501593827 @default.
• W2064443311 hasConcept C61511704 @default.
• W2064443311 hasConcept C71924100 @default.
• W2064443311 hasConcept C86803240 @default.
• W2064443311 hasConcept C89423630 @default.
• W2064443311 hasConcept C99454951 @default.
• W2064443311 hasConceptScore W2064443311C107130276 @default.
• W2064443311 hasConceptScore W2064443311C120665830 @default.
• W2064443311 hasConceptScore W2064443311C121332964 @default.
• W2064443311 hasConceptScore W2064443311C126322002 @default.
• W2064443311 hasConceptScore W2064443311C144024400 @default.
• W2064443311 hasConceptScore W2064443311C149923435 @default.
• W2064443311 hasConceptScore W2064443311C187212893 @default.
• W2064443311 hasConceptScore W2064443311C187316915 @default.
• W2064443311 hasConceptScore W2064443311C194828623 @default.
• W2064443311 hasConceptScore W2064443311C2778384902 @default.
• W2064443311 hasConceptScore W2064443311C2779159551 @default.

• next