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• W2064448524 abstract "Background and objective: It has been suggested that the rapid increase in asthma prevalence may in part be due to a decrease in the intake of dietary antioxidants, including vitamin C, vitamin E and β‐carotene. Epidemiological studies investigating the association between dietary antioxidant intake and asthma have generated inconsistent results. A meta‐analysis was undertaken to examine the association between dietary antioxidant intake and the risk of asthma. Methods: The MEDLINE database was searched for observational studies in English‐language journals from 1966 to March 2007. Data were extracted using standardized forms. Pooled odds ratios (OR) with 95% confidence intervals (CI) were calculated using a random effects model. Ten studies were eligible for inclusion. Seven studies, comprising 13 653 subjects, used asthma or wheeze as their outcome; three studies explored the effect of antioxidant intake on lung function. Results: A higher dietary intake of antioxidants was not associated with a lower risk of having asthma. The pooled OR for having asthma were 1.06 (95% CI: 0.79–1.43) for subjects with a higher dietary vitamin C intake compared with those with a lower intake; 0.88 (95% CI: 0.61–1.25) for vitamin E; and 1.12 (95% CI: 0.77–1.62) for β‐carotene. There was no significant association between dietary antioxidant intake and lung function except for a positive association between vitamin C intake and an increase in FEV 1 (29.1 mL, 95% CI: −0.4–58.6, P = 0.05). Conclusions: This meta‐analysis does not support the hypothesis that dietary intake of the antioxidants vitamins C and E and β‐carotene influences the risk of asthma." @default.
• W2064448524 created "2016-06-24" @default.
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• W2064448524 date "2008-04-10" @default.
• W2064448524 modified "2023-10-11" @default.
• W2064448524 title "Observational studies on the effect of dietary antioxidants on asthma: A meta-analysis" @default.
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• W2064448524 doi "https://doi.org/10.1111/j.1440-1843.2008.01286.x" @default.
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