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- W2064476502 abstract "There are many processes in which the neuropeptide nociceptin/orphanin FQ (N/OFQ or nociceptin) is involved in the brain. The role of nociceptin in learning and memory holds promise in modulating these processes in health and disease in the human brain. This review summarizes the body of research focused on N/OFQ and its specific receptor, the nociceptin receptor (NOP receptor), in learning and memory, and its potential mechanisms of action, in which acetylcholine, NMDA receptor, and noradrenaline may be critical. Finally, the association between NOP receptor and posttraumatic stress disorder (PTSD), a psychiatric disorder with altered fear learning, is examined as one of the potential outcomes resulting from pathological consequences of dysregulation of N/OFQ-NOP receptor in the brain." @default.
- W2064476502 created "2016-06-24" @default.
- W2064476502 creator A5039045159 @default.
- W2064476502 date "2015-10-01" @default.
- W2064476502 modified "2023-10-18" @default.
- W2064476502 title "Nociceptin and the nociceptin receptor in learning and memory" @default.
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- W2064476502 doi "https://doi.org/10.1016/j.pnpbp.2015.02.007" @default.
- W2064476502 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4458422" @default.
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