Matches in SemOpenAlex for { <https://semopenalex.org/work/W2064481947> ?p ?o ?g. }
- W2064481947 endingPage "153" @default.
- W2064481947 startingPage "146" @default.
- W2064481947 abstract "In our previous positron emission tomography studies striatal binding for both [11C]SCH23390 and [11C]N-methylspiperone (NMSP) were decreased in the rat brain on the last day of chronic (14 days) binge cocaine administration. We have found that [11C]SCH23390 binding to dopamine D1 receptors returns to saline control levels within ten days withdrawal from chronic binge cocaine and remains at control levels after 21 days withdrawal. An 18% decrease in [11C]NMSP binding to dopamine D2 receptors was observed after ten days withdrawal. However, importantly, after 21 days withdrawal [11C]NMSP binding was at saline control levels. Changes of in vivo [11C]NMSP binding required a longer abstinence period for normalization than [11C]SCH23390 binding. The apparent recovery of dopamine D2 receptors after prolonged abstinence from chronic cocaine and the different rates of normalization for dopamine D1 versus D2 receptors may be critical information for development of pharmacotherapies for cocaine dependent patients." @default.
- W2064481947 created "2016-06-24" @default.
- W2064481947 creator A5002396452 @default.
- W2064481947 creator A5005218882 @default.
- W2064481947 creator A5008578626 @default.
- W2064481947 creator A5008721084 @default.
- W2064481947 creator A5038010166 @default.
- W2064481947 creator A5039487284 @default.
- W2064481947 creator A5043811211 @default.
- W2064481947 creator A5054074865 @default.
- W2064481947 creator A5063722381 @default.
- W2064481947 creator A5066018638 @default.
- W2064481947 date "1998-08-01" @default.
- W2064481947 modified "2023-10-02" @default.
- W2064481947 title "Sustained Withdrawal Allows Normalization of In Vivo [11C]N-Methylspiperone Dopamine D2 Receptor Binding after Chronic Binge Cocaine A Positron Emission Tomography Study in Rats" @default.
- W2064481947 cites W1506870724 @default.
- W2064481947 cites W1595098454 @default.
- W2064481947 cites W1901182697 @default.
- W2064481947 cites W1931631298 @default.
- W2064481947 cites W1943544645 @default.
- W2064481947 cites W1967368280 @default.
- W2064481947 cites W1970726732 @default.
- W2064481947 cites W1977476605 @default.
- W2064481947 cites W1997829966 @default.
- W2064481947 cites W2007604257 @default.
- W2064481947 cites W2010299478 @default.
- W2064481947 cites W2027885955 @default.
- W2064481947 cites W2052193636 @default.
- W2064481947 cites W2058213757 @default.
- W2064481947 cites W2077707065 @default.
- W2064481947 cites W2079256134 @default.
- W2064481947 cites W2095217951 @default.
- W2064481947 cites W2136619214 @default.
- W2064481947 cites W222718589 @default.
- W2064481947 cites W2255544421 @default.
- W2064481947 cites W2276492075 @default.
- W2064481947 cites W2545831032 @default.
- W2064481947 cites W2626068026 @default.
- W2064481947 cites W2186000892 @default.
- W2064481947 doi "https://doi.org/10.1016/s0893-133x(98)00009-8" @default.
- W2064481947 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9629568" @default.
- W2064481947 hasPublicationYear "1998" @default.
- W2064481947 type Work @default.
- W2064481947 sameAs 2064481947 @default.
- W2064481947 citedByCount "51" @default.
- W2064481947 countsByYear W20644819472012 @default.
- W2064481947 countsByYear W20644819472013 @default.
- W2064481947 countsByYear W20644819472014 @default.
- W2064481947 countsByYear W20644819472016 @default.
- W2064481947 countsByYear W20644819472018 @default.
- W2064481947 countsByYear W20644819472019 @default.
- W2064481947 countsByYear W20644819472020 @default.
- W2064481947 countsByYear W20644819472021 @default.
- W2064481947 crossrefType "journal-article" @default.
- W2064481947 hasAuthorship W2064481947A5002396452 @default.
- W2064481947 hasAuthorship W2064481947A5005218882 @default.
- W2064481947 hasAuthorship W2064481947A5008578626 @default.
- W2064481947 hasAuthorship W2064481947A5008721084 @default.
- W2064481947 hasAuthorship W2064481947A5038010166 @default.
- W2064481947 hasAuthorship W2064481947A5039487284 @default.
- W2064481947 hasAuthorship W2064481947A5043811211 @default.
- W2064481947 hasAuthorship W2064481947A5054074865 @default.
- W2064481947 hasAuthorship W2064481947A5063722381 @default.
- W2064481947 hasAuthorship W2064481947A5066018638 @default.
- W2064481947 hasBestOaLocation W20644819471 @default.
- W2064481947 hasConcept C120069818 @default.
- W2064481947 hasConcept C126322002 @default.
- W2064481947 hasConcept C134018914 @default.
- W2064481947 hasConcept C170493617 @default.
- W2064481947 hasConcept C44208683 @default.
- W2064481947 hasConcept C513476851 @default.
- W2064481947 hasConcept C71924100 @default.
- W2064481947 hasConceptScore W2064481947C120069818 @default.
- W2064481947 hasConceptScore W2064481947C126322002 @default.
- W2064481947 hasConceptScore W2064481947C134018914 @default.
- W2064481947 hasConceptScore W2064481947C170493617 @default.
- W2064481947 hasConceptScore W2064481947C44208683 @default.
- W2064481947 hasConceptScore W2064481947C513476851 @default.
- W2064481947 hasConceptScore W2064481947C71924100 @default.
- W2064481947 hasIssue "2" @default.
- W2064481947 hasLocation W20644819471 @default.
- W2064481947 hasLocation W20644819472 @default.
- W2064481947 hasOpenAccess W2064481947 @default.
- W2064481947 hasPrimaryLocation W20644819471 @default.
- W2064481947 hasRelatedWork W1984070948 @default.
- W2064481947 hasRelatedWork W1992786090 @default.
- W2064481947 hasRelatedWork W1994302115 @default.
- W2064481947 hasRelatedWork W2007803992 @default.
- W2064481947 hasRelatedWork W2034014095 @default.
- W2064481947 hasRelatedWork W2063619316 @default.
- W2064481947 hasRelatedWork W2168345297 @default.
- W2064481947 hasRelatedWork W2598358607 @default.
- W2064481947 hasRelatedWork W2924419777 @default.
- W2064481947 hasRelatedWork W4224302975 @default.
- W2064481947 hasVolume "19" @default.
- W2064481947 isParatext "false" @default.
- W2064481947 isRetracted "false" @default.
- W2064481947 magId "2064481947" @default.