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- W2064496997 abstract "Abstract A number of independently isolated mutants of herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2), selected for their inability to code for the enzyme deoxypyrimidine kinase (dPyK− mutants), have been analyzed for their ability to take part in interallelic complementation. Such interactions have been found not only between different mutants of the same strains of HSV-1, but also between mutants of different strains. dPyK− mutants of HSV-1 also complement a dPyK− mutant of HSV-2. The mutants have been classified into four groups by their genetic behaviour. In addition, mutants which take part in interallic complementation, on mixed infection with wild-type virus, interfere with the production of wild-type deoxypyrimidine kinase, while mutants which show no interactions have no such interfering properties." @default.
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- W2064496997 date "1978-03-01" @default.
- W2064496997 modified "2023-09-25" @default.
- W2064496997 title "Interallelic complementation of mutants of herpes simplex virus deficient in deoxypyrimidine kinase activity" @default.
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- W2064496997 doi "https://doi.org/10.1016/0042-6822(78)90415-4" @default.
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