Matches in SemOpenAlex for { <https://semopenalex.org/work/W2064570904> ?p ?o ?g. }
- W2064570904 endingPage "350" @default.
- W2064570904 startingPage "341" @default.
- W2064570904 abstract "The effect of diltiazem was studied in a new model of myocardial ischaemia in which in addition to a critical constriction of the left circumflex branch (LCX), the left anterior descending coronary artery (LAD) was suddenly occluded. This model is probably more relevant to the clinical situation in which multivessel coronary artery disease is common. In this model diltiazem exerted a beneficial effect, manifested by an increase in myocardial blood flow (MBF) within the stenosed area of the LCX; by a marked reduction of the enhanced preload (LVEDP); by a diminution of the inhomogeneity of electrical activation and by a decrease in ST-segment elevation. Diltiazem also caused a significant reduction both in the number of extrasystoles and in the incidence of ventricular fibrillation. Increased MBF within the stenosed area was associated with enhanced blood flow to the ischaemic myocardium, i.e. diltiazem directed flow to the ischaemic zone by improvement of the collateral circulation. The beneficial electrophysiological changes caused by diltiazem are probably at least partly due to the drug-induced improvement of myocardial blood supply to the ischaemic area." @default.
- W2064570904 created "2016-06-24" @default.
- W2064570904 creator A5059113553 @default.
- W2064570904 creator A5059589910 @default.
- W2064570904 creator A5060660547 @default.
- W2064570904 date "1985-10-01" @default.
- W2064570904 modified "2023-10-16" @default.
- W2064570904 title "Importance of myocardial blood flow changes in the protective action of diltiazem in a new model of myocardial ischaemia" @default.
- W2064570904 cites W1561174251 @default.
- W2064570904 cites W1764202840 @default.
- W2064570904 cites W1770217747 @default.
- W2064570904 cites W179255244 @default.
- W2064570904 cites W1963923234 @default.
- W2064570904 cites W1968497234 @default.
- W2064570904 cites W1982081382 @default.
- W2064570904 cites W1991772915 @default.
- W2064570904 cites W1995542407 @default.
- W2064570904 cites W1998104311 @default.
- W2064570904 cites W2003095803 @default.
- W2064570904 cites W2010971748 @default.
- W2064570904 cites W2013227026 @default.
- W2064570904 cites W2017604806 @default.
- W2064570904 cites W2019996245 @default.
- W2064570904 cites W2034658133 @default.
- W2064570904 cites W2042765969 @default.
- W2064570904 cites W2047249729 @default.
- W2064570904 cites W2050049694 @default.
- W2064570904 cites W2051413992 @default.
- W2064570904 cites W2053762563 @default.
- W2064570904 cites W2056804541 @default.
- W2064570904 cites W2070668493 @default.
- W2064570904 cites W2085023486 @default.
- W2064570904 cites W2089135808 @default.
- W2064570904 cites W2092947498 @default.
- W2064570904 cites W2094007606 @default.
- W2064570904 cites W2102896366 @default.
- W2064570904 cites W2141470258 @default.
- W2064570904 cites W2173520866 @default.
- W2064570904 cites W2255216652 @default.
- W2064570904 cites W2413818154 @default.
- W2064570904 cites W2417190567 @default.
- W2064570904 cites W2418628105 @default.
- W2064570904 cites W2425510151 @default.
- W2064570904 cites W4230820398 @default.
- W2064570904 cites W4243411838 @default.
- W2064570904 doi "https://doi.org/10.1111/j.1476-5381.1985.tb08902.x" @default.
- W2064570904 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1916689" @default.
- W2064570904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4052733" @default.
- W2064570904 hasPublicationYear "1985" @default.
- W2064570904 type Work @default.
- W2064570904 sameAs 2064570904 @default.
- W2064570904 citedByCount "17" @default.
- W2064570904 countsByYear W20645709042015 @default.
- W2064570904 countsByYear W20645709042022 @default.
- W2064570904 crossrefType "journal-article" @default.
- W2064570904 hasAuthorship W2064570904A5059113553 @default.
- W2064570904 hasAuthorship W2064570904A5059589910 @default.
- W2064570904 hasAuthorship W2064570904A5060660547 @default.
- W2064570904 hasBestOaLocation W20645709042 @default.
- W2064570904 hasConcept C126322002 @default.
- W2064570904 hasConcept C158846371 @default.
- W2064570904 hasConcept C164705383 @default.
- W2064570904 hasConcept C178853913 @default.
- W2064570904 hasConcept C2776157398 @default.
- W2064570904 hasConcept C2776599846 @default.
- W2064570904 hasConcept C2776741139 @default.
- W2064570904 hasConcept C48277249 @default.
- W2064570904 hasConcept C500558357 @default.
- W2064570904 hasConcept C519063684 @default.
- W2064570904 hasConcept C541997718 @default.
- W2064570904 hasConcept C71924100 @default.
- W2064570904 hasConceptScore W2064570904C126322002 @default.
- W2064570904 hasConceptScore W2064570904C158846371 @default.
- W2064570904 hasConceptScore W2064570904C164705383 @default.
- W2064570904 hasConceptScore W2064570904C178853913 @default.
- W2064570904 hasConceptScore W2064570904C2776157398 @default.
- W2064570904 hasConceptScore W2064570904C2776599846 @default.
- W2064570904 hasConceptScore W2064570904C2776741139 @default.
- W2064570904 hasConceptScore W2064570904C48277249 @default.
- W2064570904 hasConceptScore W2064570904C500558357 @default.
- W2064570904 hasConceptScore W2064570904C519063684 @default.
- W2064570904 hasConceptScore W2064570904C541997718 @default.
- W2064570904 hasConceptScore W2064570904C71924100 @default.
- W2064570904 hasIssue "2" @default.
- W2064570904 hasLocation W20645709041 @default.
- W2064570904 hasLocation W20645709042 @default.
- W2064570904 hasLocation W20645709043 @default.
- W2064570904 hasLocation W20645709044 @default.
- W2064570904 hasOpenAccess W2064570904 @default.
- W2064570904 hasPrimaryLocation W20645709041 @default.
- W2064570904 hasRelatedWork W2013137210 @default.
- W2064570904 hasRelatedWork W2044770158 @default.
- W2064570904 hasRelatedWork W2064570904 @default.
- W2064570904 hasRelatedWork W2094662258 @default.
- W2064570904 hasRelatedWork W2277929193 @default.
- W2064570904 hasRelatedWork W2330473688 @default.
- W2064570904 hasRelatedWork W2350950723 @default.
- W2064570904 hasRelatedWork W2411035412 @default.