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• W2064621425 endingPage "295" @default.
• W2064621425 startingPage "290" @default.
• W2064621425 abstract "In recent years, considerable attention has been given to chitosan-based materials and their applications in the field of tissue engineering. However, the techniques proposed until now for the formation of chitosan scaffolds present some limitations such as: they are very time-consuming, use organic solvents, have difficulties in the obtainment and preservation of various levels of porosity and the 3-D structure. In this work, a new SC-CO2 assisted process for the production of chitosan scaffolds is proposed; it consists of three steps: formation of a chitosan hydrogel by thermally induced phase separation; substitution of water with a suitable solvent; drying of the gel using SC-CO2. Using this process, we produced chitosan nanostructured networks with filaments diameters around 50 nm, without any collapse of the gel nanostructure, characterized by a high porosity (>91%) and high compressive modulus (150 kPa)." @default.
• W2064621425 created "2016-06-24" @default.
• W2064621425 creator A5001813839 @default.
• W2064621425 creator A5047442858 @default.
• W2064621425 creator A5052967488 @default.
• W2064621425 date "2010-09-01" @default.
• W2064621425 modified "2023-10-18" @default.
• W2064621425 title "Generation of chitosan nanoporous structures for tissue engineering applications using a supercritical fluid assisted process" @default.
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• W2064621425 doi "https://doi.org/10.1016/j.supflu.2010.05.014" @default.
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