Matches in SemOpenAlex for { <https://semopenalex.org/work/W2064668114> ?p ?o ?g. }
- W2064668114 abstract "Repeated morphine administration leads to molecular alterations of the neural circuitry in the locus coeruleus and nucleus accumbens. These changes include increased activity of several components of the cAMP signaling pathway that are thought to be associated with psychological and somatic signs of opiate withdrawal. The neuropeptide galanin has been shown to attenuate cAMP signaling in multiple cell types. The current study demonstrates that acute galanin treatment blocks the consequences of increased cAMP signaling following chronic opiate administration and withdrawal in Cath.a cells and primary cultures of striatal neurons as measured by phosphorylation of the transcription factor cAMP regulatory element-binding protein (CREB). In addition, galanin-mediated attenuation of CREB phosphorylation is independent of galanin-induced extracellular signal-regulated kinase (ERK) 1/2 phosphorylation in Cath.a cells. These data suggest that galanin receptors may serve as an additional potential therapeutic target for the treatment of opiate withdrawal." @default.
- W2064668114 created "2016-06-24" @default.
- W2064668114 creator A5020907559 @default.
- W2064668114 creator A5060117584 @default.
- W2064668114 creator A5065396580 @default.
- W2064668114 date "2006-02-01" @default.
- W2064668114 modified "2023-09-25" @default.
- W2064668114 title "Galanin attenuates cyclic AMP regulatory element-binding protein (CREB) phosphorylation induced by chronic morphine and naloxone challenge in Cath.a cells and primary striatal cultures" @default.
- W2064668114 cites W1496943120 @default.
- W2064668114 cites W1529247698 @default.
- W2064668114 cites W1531431930 @default.
- W2064668114 cites W1591789321 @default.
- W2064668114 cites W1775302509 @default.
- W2064668114 cites W1782902465 @default.
- W2064668114 cites W1928329059 @default.
- W2064668114 cites W1961046454 @default.
- W2064668114 cites W1975052684 @default.
- W2064668114 cites W1977251490 @default.
- W2064668114 cites W1979017418 @default.
- W2064668114 cites W1979171380 @default.
- W2064668114 cites W1982875691 @default.
- W2064668114 cites W1996864148 @default.
- W2064668114 cites W2001607934 @default.
- W2064668114 cites W2001865657 @default.
- W2064668114 cites W2004465233 @default.
- W2064668114 cites W2004922458 @default.
- W2064668114 cites W2007611402 @default.
- W2064668114 cites W2014197067 @default.
- W2064668114 cites W2017883706 @default.
- W2064668114 cites W2018762606 @default.
- W2064668114 cites W2020710396 @default.
- W2064668114 cites W2026639575 @default.
- W2064668114 cites W2032166580 @default.
- W2064668114 cites W2037444729 @default.
- W2064668114 cites W2041222055 @default.
- W2064668114 cites W2041505140 @default.
- W2064668114 cites W2042421949 @default.
- W2064668114 cites W2046298299 @default.
- W2064668114 cites W2047507533 @default.
- W2064668114 cites W2049796382 @default.
- W2064668114 cites W2051365027 @default.
- W2064668114 cites W2053763819 @default.
- W2064668114 cites W2055319462 @default.
- W2064668114 cites W2058123276 @default.
- W2064668114 cites W2065377483 @default.
- W2064668114 cites W2066264082 @default.
- W2064668114 cites W2072612746 @default.
- W2064668114 cites W2073019193 @default.
- W2064668114 cites W2078066211 @default.
- W2064668114 cites W2081524299 @default.
- W2064668114 cites W2083056701 @default.
- W2064668114 cites W2084043489 @default.
- W2064668114 cites W2090271176 @default.
- W2064668114 cites W2113983630 @default.
- W2064668114 cites W2116504386 @default.
- W2064668114 cites W2128220751 @default.
- W2064668114 cites W2129956706 @default.
- W2064668114 cites W2140257707 @default.
- W2064668114 cites W2152268051 @default.
- W2064668114 cites W2153283433 @default.
- W2064668114 cites W2169322025 @default.
- W2064668114 cites W2169357564 @default.
- W2064668114 cites W2170807563 @default.
- W2064668114 cites W2222436615 @default.
- W2064668114 cites W1754807110 @default.
- W2064668114 doi "https://doi.org/10.1111/j.1471-4159.2005.03613.x" @default.
- W2064668114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16417577" @default.
- W2064668114 hasPublicationYear "2006" @default.
- W2064668114 type Work @default.
- W2064668114 sameAs 2064668114 @default.
- W2064668114 citedByCount "13" @default.
- W2064668114 countsByYear W20646681142013 @default.
- W2064668114 countsByYear W20646681142015 @default.
- W2064668114 crossrefType "journal-article" @default.
- W2064668114 hasAuthorship W2064668114A5020907559 @default.
- W2064668114 hasAuthorship W2064668114A5060117584 @default.
- W2064668114 hasAuthorship W2064668114A5065396580 @default.
- W2064668114 hasBestOaLocation W20646681141 @default.
- W2064668114 hasConcept C104317684 @default.
- W2064668114 hasConcept C118303440 @default.
- W2064668114 hasConcept C11960822 @default.
- W2064668114 hasConcept C126322002 @default.
- W2064668114 hasConcept C134018914 @default.
- W2064668114 hasConcept C1629964 @default.
- W2064668114 hasConcept C170493617 @default.
- W2064668114 hasConcept C185592680 @default.
- W2064668114 hasConcept C19519825 @default.
- W2064668114 hasConcept C2776552330 @default.
- W2064668114 hasConcept C2778140631 @default.
- W2064668114 hasConcept C2778468602 @default.
- W2064668114 hasConcept C529278444 @default.
- W2064668114 hasConcept C55493867 @default.
- W2064668114 hasConcept C57074206 @default.
- W2064668114 hasConcept C62478195 @default.
- W2064668114 hasConcept C71924100 @default.
- W2064668114 hasConcept C86339819 @default.
- W2064668114 hasConcept C86803240 @default.
- W2064668114 hasConcept C95444343 @default.
- W2064668114 hasConcept C98274493 @default.
- W2064668114 hasConceptScore W2064668114C104317684 @default.