FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2064730289> ?p ?o ?g. }

• W2064730289 endingPage "S56???S57" @default.
• W2064730289 startingPage "S56???S57" @default.
• W2064730289 abstract "Abnormal fatigue is a common symptom in persons with multiple sclerosis (MS). In MS patients complaining of this symptomatic fatigue, it has been suggested that impaired cardiovascular function may contribute to the pathogenesis of muscle fatigue in MS. PURPOSE To determine if decreased muscle endurance in persons with MS who report symptomatic fatigue is blood flow related. METHODS Eight MS (4 f, 4 m, median EDSS = 4); and 7 age-matched control (C) subjects (4 f, 3 m) performed fatiguing isometric dorsiflexion exercise with and without arterial occlusion (suprasystolic thigh cuff inflation) of the lower leg. On the initial visit, symptomatic fatigue was measured by the Fatigue Impact Scale (FIS) and the Fatigue Severity Scale (FSS). Testing occurred on separate days separated by at least 48 hrs and was counter-balanced in a random fashion. Exercise intensity was 45% of initial maximal voluntary contraction (MVC), with a 75% duty cycle (6s contract, 2s relax), until task failure. MVC was obtained initially and immediately after task failure. Endurance time (ET) was the time to task failure. Fatigue was indicated by the post-exercise MVC to pre-exercise MVC ratio expressed as percent. RESULTS Results are mean ± SE. MS and control subjects were of similar age (MS = 48 ± 8 yrs, C = 42 ± 7 yrs). MS compared to C subjects reported more symptomatic fatigue with both FIS (MS = 62 ± 17, C = 1 ± 1, p<0.01) and FSS (MS = 4.5 ± 0.5, C = 1.7 ± 0.2, p<0.01). In exercise with occlusion, there was no difference between groups in ET (MS = 214 ± 29s, C = 227 ± 30s) or muscle fatigue (MS = 45 ± 5%, C = 40 ± 4%). In exercise without occlusion, ET was shorter in MS compared to C groups (MS = 303 ± 53s, C = 559 ± 30s, p<0.05). However, muscle fatigue (MS = 67 ± 6%, C = 62 ± 4%) was similar between groups. CONCLUSIONS When any effect of blood flow, or oxygen delivery, was removed during occlusion, ET was similar between groups. Because ET was shorter in MS compared to C when circulation was intact, we conclude that impaired blood flow (i.e., oxygen delivery) or oxygen usage during exercise in MS may be associated with decreased muscle endurance. Sponsored by the National Multiple Sclerosis Society." @default.
• W2064730289 created "2016-06-24" @default.
• W2064730289 creator A5010724321 @default.
• W2064730289 creator A5028144469 @default.
• W2064730289 creator A5052462006 @default.
• W2064730289 creator A5068949682 @default.
• W2064730289 creator A5072715569 @default.
• W2064730289 date "2005-05-01" @default.
• W2064730289 modified "2023-09-27" @default.
• W2064730289 title "Evidence For A Blood Flow Associated Limitation To Endurance In Persons With Multiple Sclerosis" @default.
• W2064730289 doi "https://doi.org/10.1097/00005768-200505001-00302" @default.
• W2064730289 hasPublicationYear "2005" @default.
• W2064730289 type Work @default.
• W2064730289 sameAs 2064730289 @default.
• W2064730289 citedByCount "0" @default.
• W2064730289 crossrefType "journal-article" @default.
• W2064730289 hasAuthorship W2064730289A5010724321 @default.
• W2064730289 hasAuthorship W2064730289A5028144469 @default.
• W2064730289 hasAuthorship W2064730289A5052462006 @default.
• W2064730289 hasAuthorship W2064730289A5068949682 @default.
• W2064730289 hasAuthorship W2064730289A5072715569 @default.
• W2064730289 hasBestOaLocation W20647302891 @default.
• W2064730289 hasConcept C103486182 @default.
• W2064730289 hasConcept C118552586 @default.
• W2064730289 hasConcept C126322002 @default.
• W2064730289 hasConcept C164705383 @default.
• W2064730289 hasConcept C1862650 @default.
• W2064730289 hasConcept C2776874296 @default.
• W2064730289 hasConcept C2777515770 @default.
• W2064730289 hasConcept C2780640218 @default.
• W2064730289 hasConcept C71924100 @default.
• W2064730289 hasConcept C99508421 @default.
• W2064730289 hasConceptScore W2064730289C103486182 @default.
• W2064730289 hasConceptScore W2064730289C118552586 @default.
• W2064730289 hasConceptScore W2064730289C126322002 @default.
• W2064730289 hasConceptScore W2064730289C164705383 @default.
• W2064730289 hasConceptScore W2064730289C1862650 @default.
• W2064730289 hasConceptScore W2064730289C2776874296 @default.
• W2064730289 hasConceptScore W2064730289C2777515770 @default.
• W2064730289 hasConceptScore W2064730289C2780640218 @default.
• W2064730289 hasConceptScore W2064730289C71924100 @default.
• W2064730289 hasConceptScore W2064730289C99508421 @default.
• W2064730289 hasIssue "Supplement" @default.
• W2064730289 hasLocation W20647302891 @default.
• W2064730289 hasLocation W20647302892 @default.
• W2064730289 hasOpenAccess W2064730289 @default.
• W2064730289 hasPrimaryLocation W20647302891 @default.
• W2064730289 hasRelatedWork W1978098000 @default.
• W2064730289 hasRelatedWork W2011108763 @default.
• W2064730289 hasRelatedWork W2043815918 @default.
• W2064730289 hasRelatedWork W2046078436 @default.
• W2064730289 hasRelatedWork W2524403369 @default.
• W2064730289 hasRelatedWork W2913310132 @default.
• W2064730289 hasRelatedWork W3035204648 @default.
• W2064730289 hasRelatedWork W3083649316 @default.
• W2064730289 hasRelatedWork W3181553747 @default.
• W2064730289 hasRelatedWork W3206662010 @default.
• W2064730289 hasVolume "37" @default.
• W2064730289 isParatext "false" @default.
• W2064730289 isRetracted "false" @default.
• W2064730289 magId "2064730289" @default.
• W2064730289 workType "article" @default.