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- W2064752246 abstract "Positron-emission tomography (PET) is a noninvasive real-time functional imaging system and is expected to be useful for the development of new drug candidates in clinical trials. For its application with preformulated liposomes, we devised an optimized [18F]-compound and developed a direct liposome modification method that we termed the “solid-phase transition method”. We were successful in using 1-[18F]fluoro-3,6-dioxatetracosane ([18F]7a) for in vivo trafficking of liposomes. This method might be a useful tool in preclinical and clinical studies of lipidic particle-related drugs." @default.
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- W2064752246 date "2007-12-01" @default.
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- W2064752246 title "Novel Amphiphilic Probes for [<sup>18</sup>F]-Radiolabeling Preformed Liposomes and Determination of Liposomal Trafficking by Positron Emission Tomography" @default.
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- W2064752246 doi "https://doi.org/10.1021/jm7010518" @default.
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