Matches in SemOpenAlex for { <https://semopenalex.org/work/W2064759877> ?p ?o ?g. }
- W2064759877 endingPage "141" @default.
- W2064759877 startingPage "129" @default.
- W2064759877 abstract "Bone marrow mensenchyme cells (BMSCs) can differentiate into endothelial progenitor cells which then migrate to injured sites for the repair of neointima, and stromal cell-derived factor-1α (SDF-1α) can mediate the migration of CXCR4 expressing stem/progenitor cells to injured sites for pair. Protein and mRNA expression of SDF-1α and CXCR4 were determined by RT-PCR, Western blot and ELISA. Immediately after common carotid artery balloon injury, the mRNA expression of SDF-1α in vascular smooth muscle cells (VSMCs) first increased and then decreased 7 days later. VSMCs transfected with SDF-1α siRNA did not express SDF-1α mRNA, but after transfection with SDF-1α siRNA, the SDF-1α content in injured VSMCs gradually returned to the baseline level. Normal BMSCs rarely expressed CXCR4 mRNA, but the CXCR4 mRNA expression on BMSCs increased significantly 4 days after common carotid artery injury and was maintained. The migration of BMSCs after artery injury was enhanced when compared with normal BMSCs, but SDF-1α siRNA transfection of VSMCs and AMD3100 treatment remarkably decreased the chemotaxis of BMSCs to VSMCs and SDF-1α, respectively. We conclude that the SDF-1α/CXCR4 axis plays an important role in the migration of BMSCs after balloon injury and can ultimately cause abnormal proliferation of the intima." @default.
- W2064759877 created "2016-06-24" @default.
- W2064759877 creator A5006343463 @default.
- W2064759877 creator A5011022104 @default.
- W2064759877 creator A5012119026 @default.
- W2064759877 creator A5084080000 @default.
- W2064759877 creator A5089909590 @default.
- W2064759877 date "2011-07-31" @default.
- W2064759877 modified "2023-10-14" @default.
- W2064759877 title "Effects of SDF-1α/CXCR4 on vascular smooth muscle cells and bone marrow mesenchymal cells in a rat carotid artery balloon injury model" @default.
- W2064759877 cites W1481422886 @default.
- W2064759877 cites W1499075785 @default.
- W2064759877 cites W1504660023 @default.
- W2064759877 cites W1547715367 @default.
- W2064759877 cites W1586474677 @default.
- W2064759877 cites W1965304525 @default.
- W2064759877 cites W1969986792 @default.
- W2064759877 cites W1981263092 @default.
- W2064759877 cites W1989035987 @default.
- W2064759877 cites W2005975965 @default.
- W2064759877 cites W2013788023 @default.
- W2064759877 cites W2016931709 @default.
- W2064759877 cites W2018526639 @default.
- W2064759877 cites W2053704719 @default.
- W2064759877 cites W2064063264 @default.
- W2064759877 cites W2090412760 @default.
- W2064759877 cites W2098385948 @default.
- W2064759877 cites W2098444281 @default.
- W2064759877 cites W2100566933 @default.
- W2064759877 cites W2104179984 @default.
- W2064759877 cites W2104221257 @default.
- W2064759877 cites W2105840074 @default.
- W2064759877 cites W2108875285 @default.
- W2064759877 cites W2114741924 @default.
- W2064759877 cites W2116059256 @default.
- W2064759877 cites W2120523077 @default.
- W2064759877 cites W2127340807 @default.
- W2064759877 cites W2147425697 @default.
- W2064759877 cites W2149604229 @default.
- W2064759877 cites W2149729267 @default.
- W2064759877 cites W2157062970 @default.
- W2064759877 cites W2158979977 @default.
- W2064759877 cites W2159999899 @default.
- W2064759877 cites W2164470216 @default.
- W2064759877 cites W2169221044 @default.
- W2064759877 cites W4245635197 @default.
- W2064759877 cites W4251035763 @default.
- W2064759877 cites W56280360 @default.
- W2064759877 doi "https://doi.org/10.2478/v10136-011-0001-8" @default.
- W2064759877 hasPublicationYear "2011" @default.
- W2064759877 type Work @default.
- W2064759877 sameAs 2064759877 @default.
- W2064759877 citedByCount "2" @default.
- W2064759877 countsByYear W20647598772015 @default.
- W2064759877 countsByYear W20647598772022 @default.
- W2064759877 crossrefType "journal-article" @default.
- W2064759877 hasAuthorship W2064759877A5006343463 @default.
- W2064759877 hasAuthorship W2064759877A5011022104 @default.
- W2064759877 hasAuthorship W2064759877A5012119026 @default.
- W2064759877 hasAuthorship W2064759877A5084080000 @default.
- W2064759877 hasAuthorship W2064759877A5089909590 @default.
- W2064759877 hasBestOaLocation W20647598771 @default.
- W2064759877 hasConcept C126322002 @default.
- W2064759877 hasConcept C141071460 @default.
- W2064759877 hasConcept C142724271 @default.
- W2064759877 hasConcept C16930146 @default.
- W2064759877 hasConcept C198826908 @default.
- W2064759877 hasConcept C201750760 @default.
- W2064759877 hasConcept C2775944032 @default.
- W2064759877 hasConcept C2777339539 @default.
- W2064759877 hasConcept C2778283817 @default.
- W2064759877 hasConcept C2778583881 @default.
- W2064759877 hasConcept C2779395532 @default.
- W2064759877 hasConcept C2780007613 @default.
- W2064759877 hasConcept C28328180 @default.
- W2064759877 hasConcept C2992686903 @default.
- W2064759877 hasConcept C49453240 @default.
- W2064759877 hasConcept C54009773 @default.
- W2064759877 hasConcept C54355233 @default.
- W2064759877 hasConcept C64943373 @default.
- W2064759877 hasConcept C71924100 @default.
- W2064759877 hasConcept C81885089 @default.
- W2064759877 hasConcept C86803240 @default.
- W2064759877 hasConcept C95444343 @default.
- W2064759877 hasConceptScore W2064759877C126322002 @default.
- W2064759877 hasConceptScore W2064759877C141071460 @default.
- W2064759877 hasConceptScore W2064759877C142724271 @default.
- W2064759877 hasConceptScore W2064759877C16930146 @default.
- W2064759877 hasConceptScore W2064759877C198826908 @default.
- W2064759877 hasConceptScore W2064759877C201750760 @default.
- W2064759877 hasConceptScore W2064759877C2775944032 @default.
- W2064759877 hasConceptScore W2064759877C2777339539 @default.
- W2064759877 hasConceptScore W2064759877C2778283817 @default.
- W2064759877 hasConceptScore W2064759877C2778583881 @default.
- W2064759877 hasConceptScore W2064759877C2779395532 @default.
- W2064759877 hasConceptScore W2064759877C2780007613 @default.
- W2064759877 hasConceptScore W2064759877C28328180 @default.
- W2064759877 hasConceptScore W2064759877C2992686903 @default.