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- W2064794807 endingPage "189" @default.
- W2064794807 startingPage "175" @default.
- W2064794807 abstract "Probiotic microorganisms have historically been used to rebalance disturbed intestinal microbiota and to diminish gastrointestinal disorders, such as diarrhea or inflammatory bowel diseases (e.g., Crohn's disease and ulcerative colitis). Recent studies explore the potential for expanded uses of probiotics on medical disorders that increase the risk of developing cardiovascular diseases and diabetes, such as obesity, hypercholesterolemia, arterial hypertension, and metabolic disturbances such as hyperhomocysteinemia and oxidative stress. This review aims at summarizing the proposed molecular and cellular mechanisms involved in probiotic–host interactions and to identify the nature of the resulting beneficial effects. Specific probiotic strains can act by modulating immune response, by producing particular molecules or releasing biopeptides, and by modulating nervous system activity. To date, the majority of studies have been conducted in animal models. New investigations on the related mechanisms in humans need to be carried out to better enable targeted and effective use of the broad variety of probiotic strains." @default.
- W2064794807 created "2016-06-24" @default.
- W2064794807 creator A5001959844 @default.
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- W2064794807 creator A5076433007 @default.
- W2064794807 creator A5082159181 @default.
- W2064794807 creator A5083701333 @default.
- W2064794807 date "2013-11-04" @default.
- W2064794807 modified "2023-10-08" @default.
- W2064794807 title "Impact of Probiotics on Risk Factors for Cardiovascular Diseases. A Review" @default.
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