Matches in SemOpenAlex for { <https://semopenalex.org/work/W2064832882> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2064832882 endingPage "318???327" @default.
- W2064832882 startingPage "318???327" @default.
- W2064832882 abstract "Twenty-four patients with refractory affective disorders who were taking carbamazepine were followed in an open-label fashion for an average of 4 years. Carbamazepine, usually in combination with lithium and other previously ineffective medications, reduced the number and severity of manic and depressive episodes. An overall illness index of morbidity (duration x severity) decreased 72% in the first year and 66% in the second year of carbamazepine treatment. One-half of the patients (N = 11) who were followed for more than 2 years showed a pattern of continued improvement (stable); the other half showed loss of prophylaxis (escape). Those showing the escape pattern had a more rapidly deteriorating course of illness in the 4 years before the study than those showing the stable improvement. Clinical and mechanistic implications of these findings are discussed, including the phenomenon of contingent tolerance as a possible explanation for the emergence of loss of efficacy in a subgroup of patients." @default.
- W2064832882 created "2016-06-24" @default.
- W2064832882 creator A5006895356 @default.
- W2064832882 creator A5053329398 @default.
- W2064832882 creator A5054719819 @default.
- W2064832882 creator A5089088835 @default.
- W2064832882 date "1990-10-01" @default.
- W2064832882 modified "2023-10-14" @default.
- W2064832882 title "Carbamazepine Prophylaxis in Refractory Affective" @default.
- W2064832882 doi "https://doi.org/10.1097/00004714-199010000-00003" @default.
- W2064832882 hasPublicationYear "1990" @default.
- W2064832882 type Work @default.
- W2064832882 sameAs 2064832882 @default.
- W2064832882 citedByCount "63" @default.
- W2064832882 countsByYear W20648328822015 @default.
- W2064832882 crossrefType "journal-article" @default.
- W2064832882 hasAuthorship W2064832882A5006895356 @default.
- W2064832882 hasAuthorship W2064832882A5053329398 @default.
- W2064832882 hasAuthorship W2064832882A5054719819 @default.
- W2064832882 hasAuthorship W2064832882A5089088835 @default.
- W2064832882 hasConcept C118552586 @default.
- W2064832882 hasConcept C121332964 @default.
- W2064832882 hasConcept C126322002 @default.
- W2064832882 hasConcept C142424586 @default.
- W2064832882 hasConcept C187212893 @default.
- W2064832882 hasConcept C2778186239 @default.
- W2064832882 hasConcept C2778541603 @default.
- W2064832882 hasConcept C2779253243 @default.
- W2064832882 hasConcept C71924100 @default.
- W2064832882 hasConcept C87355193 @default.
- W2064832882 hasConceptScore W2064832882C118552586 @default.
- W2064832882 hasConceptScore W2064832882C121332964 @default.
- W2064832882 hasConceptScore W2064832882C126322002 @default.
- W2064832882 hasConceptScore W2064832882C142424586 @default.
- W2064832882 hasConceptScore W2064832882C187212893 @default.
- W2064832882 hasConceptScore W2064832882C2778186239 @default.
- W2064832882 hasConceptScore W2064832882C2778541603 @default.
- W2064832882 hasConceptScore W2064832882C2779253243 @default.
- W2064832882 hasConceptScore W2064832882C71924100 @default.
- W2064832882 hasConceptScore W2064832882C87355193 @default.
- W2064832882 hasIssue "5" @default.
- W2064832882 hasLocation W20648328821 @default.
- W2064832882 hasOpenAccess W2064832882 @default.
- W2064832882 hasPrimaryLocation W20648328821 @default.
- W2064832882 hasRelatedWork W1982094616 @default.
- W2064832882 hasRelatedWork W1985937992 @default.
- W2064832882 hasRelatedWork W2013360878 @default.
- W2064832882 hasRelatedWork W2022746100 @default.
- W2064832882 hasRelatedWork W2022976035 @default.
- W2064832882 hasRelatedWork W2165990107 @default.
- W2064832882 hasRelatedWork W2389844078 @default.
- W2064832882 hasRelatedWork W2390115927 @default.
- W2064832882 hasRelatedWork W2429460896 @default.
- W2064832882 hasRelatedWork W2185975764 @default.
- W2064832882 hasVolume "10" @default.
- W2064832882 isParatext "false" @default.
- W2064832882 isRetracted "false" @default.
- W2064832882 magId "2064832882" @default.
- W2064832882 workType "article" @default.