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• W2064910216 abstract "Elevated alcohol consumption is associated with an increased risk of cancer. Reasons for this association are not well established but may relate to alterations in cholesterol, vitamin A (carotene and retinol), and vitamin E metabolism, since low levels of these factors have been linked to risk of cancer. Blood levels of cholesterol, carotene, retinol, and vitamin E were determined in 192 male alcoholics entering into an alcohol detoxification program. Compared to nonalcoholic populations, their cholesterol (187 mg/dl) and carotene (94 μg/dl) concentrations were markedly reduced at entrance; however, abstinence of 33 days returned both to normal levels. In contrast, the retinol and vitamin E levels were within the normal range at baseline and remained relatively stable throughout rehabilitation. Of particular interest was that the low density lipoprotein cholesterol was highly correlated with carotene (r = +0.40, whites, r = +0.54, blacks). The results suggest that alterations in the metabolism of cholesterol and carotene, due to alcohol intake, may partially account for the relationship of alcohol to increased cancer risk." @default.
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• W2064910216 date "1986-05-01" @default.
• W2064910216 modified "2023-10-17" @default.
• W2064910216 title "Lipoprotein cholesterol, vitamin A, and vitamin E in an alcoholic population" @default.
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• W2064910216 doi "https://doi.org/10.1002/1097-0142(19860501)57:9<1798::aid-cncr2820570915>3.0.co;2-x" @default.
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