Matches in SemOpenAlex for { <https://semopenalex.org/work/W2064930805> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2064930805 endingPage "21" @default.
- W2064930805 startingPage "18" @default.
- W2064930805 abstract "Thirteen patients (7 male, 9 female) aged 22 bis 71 years (x = 55 years) with acute non-lymphocytic leukemia and contraindications for anthracyclin therapy were treated with combined chemotherapy using m-amsacrine primarily or in relapse. The main reasons for avoiding cardiotoxic substances were overt cardiac insufficiency and former administration of daunorubicin with more than 540 mg/m2 body surface area. Amsacrine was combined with 6-thioguanine, VP 16–213 and cytosine arabinoside in conventional or high dosage. Eight out of 13 patients (62%) achieved complete remission after one or two courses of chemotherapy. One patient showed partial remission and could be brought into complete remission with another chemotherapy using high-dose ara-C and mitoxantrone. Three patients died in aplasia after chemotherapy and 1 other patient had to be regarded as a complete non-responder. Remission duration and survival time for the 8 successfully-treated patients so far is 1–12 months; however, medians have not yet been reached, since only one of the eight patients relapsed after 6 months of complete remission. These data indicate a high efficacy of m-amsacrine in combined chemotherapy for acute non-lymphocytic leukemia in high-risk patients with contraindications for anthracyclins." @default.
- W2064930805 created "2016-06-24" @default.
- W2064930805 creator A5009983233 @default.
- W2064930805 creator A5045145638 @default.
- W2064930805 creator A5078376583 @default.
- W2064930805 creator A5079017739 @default.
- W2064930805 date "1987-01-01" @default.
- W2064930805 modified "2023-10-14" @default.
- W2064930805 title "Combined Chemotherapy with m-Amsacrine in High-Risk Patients with Acute Non-Lymphocytic Leukemia" @default.
- W2064930805 doi "https://doi.org/10.1159/000216361" @default.
- W2064930805 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3295621" @default.
- W2064930805 hasPublicationYear "1987" @default.
- W2064930805 type Work @default.
- W2064930805 sameAs 2064930805 @default.
- W2064930805 citedByCount "1" @default.
- W2064930805 crossrefType "journal-article" @default.
- W2064930805 hasAuthorship W2064930805A5009983233 @default.
- W2064930805 hasAuthorship W2064930805A5045145638 @default.
- W2064930805 hasAuthorship W2064930805A5078376583 @default.
- W2064930805 hasAuthorship W2064930805A5079017739 @default.
- W2064930805 hasConcept C126322002 @default.
- W2064930805 hasConcept C141071460 @default.
- W2064930805 hasConcept C2776694085 @default.
- W2064930805 hasConcept C2776863199 @default.
- W2064930805 hasConcept C2778119113 @default.
- W2064930805 hasConcept C2778461978 @default.
- W2064930805 hasConcept C2780500152 @default.
- W2064930805 hasConcept C2780923524 @default.
- W2064930805 hasConcept C2781021840 @default.
- W2064930805 hasConcept C2781107101 @default.
- W2064930805 hasConcept C2909962599 @default.
- W2064930805 hasConcept C3018657049 @default.
- W2064930805 hasConcept C71924100 @default.
- W2064930805 hasConcept C90924648 @default.
- W2064930805 hasConceptScore W2064930805C126322002 @default.
- W2064930805 hasConceptScore W2064930805C141071460 @default.
- W2064930805 hasConceptScore W2064930805C2776694085 @default.
- W2064930805 hasConceptScore W2064930805C2776863199 @default.
- W2064930805 hasConceptScore W2064930805C2778119113 @default.
- W2064930805 hasConceptScore W2064930805C2778461978 @default.
- W2064930805 hasConceptScore W2064930805C2780500152 @default.
- W2064930805 hasConceptScore W2064930805C2780923524 @default.
- W2064930805 hasConceptScore W2064930805C2781021840 @default.
- W2064930805 hasConceptScore W2064930805C2781107101 @default.
- W2064930805 hasConceptScore W2064930805C2909962599 @default.
- W2064930805 hasConceptScore W2064930805C3018657049 @default.
- W2064930805 hasConceptScore W2064930805C71924100 @default.
- W2064930805 hasConceptScore W2064930805C90924648 @default.
- W2064930805 hasIssue "1" @default.
- W2064930805 hasLocation W20649308051 @default.
- W2064930805 hasLocation W20649308052 @default.
- W2064930805 hasOpenAccess W2064930805 @default.
- W2064930805 hasPrimaryLocation W20649308051 @default.
- W2064930805 hasRelatedWork W1985709824 @default.
- W2064930805 hasRelatedWork W2002667718 @default.
- W2064930805 hasRelatedWork W2026799206 @default.
- W2064930805 hasRelatedWork W2046873907 @default.
- W2064930805 hasRelatedWork W2064930805 @default.
- W2064930805 hasRelatedWork W2404703750 @default.
- W2064930805 hasRelatedWork W2406677972 @default.
- W2064930805 hasRelatedWork W2426236262 @default.
- W2064930805 hasRelatedWork W2468695245 @default.
- W2064930805 hasRelatedWork W2495138153 @default.
- W2064930805 hasVolume "10" @default.
- W2064930805 isParatext "false" @default.
- W2064930805 isRetracted "false" @default.
- W2064930805 magId "2064930805" @default.
- W2064930805 workType "article" @default.