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- W2064973269 abstract "To determine the expression of macrophage inhibitory protein-3beta (MIP-3beta), a potential chemoattractant for endometrial natural killer (NK) cells, in the human endometrium.An experimental study.University department of obstetrics and gynecology.Thirty-seven fertile women with regular menstrual cycles and nonpathological endometrium, undergoing hysterectomy.Endometrium was obtained from operative samples.Paraffin-embedded endometrium was immunostained to determine the localization of MIP-3beta. The number of NK cells was counted in 10 nonoverlapping stromal areas. The MIP-3beta concentration in the homogenized endometrium was determined by ELISA.Immunoreactivity for MIP-3beta was observed in the surface epithelia, glandular epithelia, and stroma with some menstrual cycle-dependent fluctuation. The MIP-3beta concentration was significantly higher in the late secretory phase than in the other phases. It showed a trend toward correlation with the number of endometrial NK cells.MIP-3beta was expressed in the human endometrium, but our results could not strongly support the hypothesis that MIP-3beta is a potential chemoattractant for endometrial NK cells." @default.
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- W2064973269 date "2004-03-01" @default.
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- W2064973269 title "Expression of macrophage inflammatory protein-3β in human endometrium throughout the menstrual cycle" @default.
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- W2064973269 doi "https://doi.org/10.1016/j.fertnstert.2003.09.036" @default.
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