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- W2064982083 abstract "The inhibitor of kB kinase (IKK) complex, a critical positive regulator of nuclear factor kappaB (NF-kappaB) signaling and immune function, can be activated in vitro by polyubiquitin chains. The modification of signaling intermediates by polyubiquitin and their association with ubiquitin-binding domain-containing proteins within multimolecular signaling complexes therefore represent a potential mechanism for activation of IKK and NF-kappaB in vivo." @default.
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- W2064982083 date "2009-10-08" @default.
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- W2064982083 title "Direct Activation of Protein Kinases by Ubiquitin" @default.
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- W2064982083 doi "https://doi.org/10.1093/jmcb/mjp029" @default.
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