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• W2065002435 abstract "La constitution de réservoirs pour le VIH-1 intégré de manière latente s’établit très précocement au cours de l’infection et constitue un obstacle majeur à son éradication. Celle-ci n’est ainsi envisageable que si une purge de ces réservoirs est associée à une multithérapie active. Confrontée à l’absence d’une vaccination efficace contre le VIH-1, qui constitue toujours un important défi pour les immunologistes, la guérison des malades passera par le développement de stratégies originales qui devront tenir compte à la fois des phénomènes de latence virale et de réplication chronique, mais aussi de l’existence de sanctuaires tissulaires." @default.
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• W2065002435 date "2010-03-01" @default.
• W2065002435 modified "2023-10-15" @default.
• W2065002435 title "Un virus tapi dans l’ombre : les bases moléculaires de la latence du VIH-1" @default.
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• W2065002435 doi "https://doi.org/10.1051/medsci/2010263291" @default.
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