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- W2065046968 abstract "To investigate the association of CYP2C9*3 and *6 with hyperlipidaemia in Chinese.Four hundred and seventy-six Chinese participated in the study, including 211 uncomplicated hyperlipidaemic patients and 265 healthy controls. PCR-RFLP was used to identify CYP2C9*3 and *6.CYP2C9*6 was not detected in this study. The allelic frequency of CYP2C9*3 was 0.039 (95% CI 0.022, 0.056). A nonsignificant difference existed in CYP2C9*3 frequencies between males and females (P = 0.605, OR = 1.194, 95% CI 0.610, 2.336), patients and controls (P = 0.063, OR = 0.506, 95% CI 0.244, 1.049) in the total population. However, in the female group, CYP2C9*3 frequency in patients with hyperlipidaemia was significantly lower than that in controls (P < 0.0001, OR = 0.062, 95% CI 0.008, 0.476).The association of CYP2C9*3 with hyperlipidaemia was specific for females in this Chinese population." @default.
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- W2065046968 date "2005-09-13" @default.
- W2065046968 modified "2023-09-26" @default.
- W2065046968 title "Gender specific association of CYP2C9*3 with hyperlipidaemia in Chinese" @default.
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- W2065046968 doi "https://doi.org/10.1111/j.1365-2125.2005.02498.x" @default.
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