Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065065847> ?p ?o ?g. }
- W2065065847 endingPage "58" @default.
- W2065065847 startingPage "49" @default.
- W2065065847 abstract "The increasing use of carbon nanotubes (CNTs) in biomedical applications has garnered a great concern on their potential negative effects to human health. CNTs have been reported to potentially disrupt normal neuronal function and they were speculated to accumulate and cause brain damage, although a lot of distinct and exceptional properties and potential wide applications have been associated with this material in neurobiology. Fe impurities strapped inside the CNTs may be partially responsible for neurotoxicity generation. In the present study, we selected rat pheochromocytoma (PC12) cells to investigate and compare the effects of two kinds of multiwall carbon nanotubes (MWCNTs) with different concentrations of Fe impurities which usually come from the massive production of CNTs by chemical vapor deposition. Exposure to Fe-high MWCNTs can reduce cell viability and increase cytoskeletal disruption of undifferentiated PC12 cells, diminish the ability to form mature neurites, and then adversely influence the neuronal dopaminergic phenotype in NGF-treated PC-12 cells. The present results highlight the critical role of iron residue in the adverse response to MWCNTs exposure in neural cells. These findings provide useful information for understanding the toxicity and safe application of carbon nanotubes." @default.
- W2065065847 created "2016-06-24" @default.
- W2065065847 creator A5007293606 @default.
- W2065065847 creator A5024938458 @default.
- W2065065847 creator A5040060805 @default.
- W2065065847 creator A5049078993 @default.
- W2065065847 creator A5053453125 @default.
- W2065065847 creator A5063409154 @default.
- W2065065847 creator A5073108451 @default.
- W2065065847 creator A5076901473 @default.
- W2065065847 creator A5077426352 @default.
- W2065065847 date "2013-11-01" @default.
- W2065065847 modified "2023-10-16" @default.
- W2065065847 title "Inhibitory effects of multiwall carbon nanotubes with high iron impurity on viability and neuronal differentiation in cultured PC12 cells" @default.
- W2065065847 cites W1480889861 @default.
- W2065065847 cites W1909728874 @default.
- W2065065847 cites W1970282680 @default.
- W2065065847 cites W1970587959 @default.
- W2065065847 cites W1974212976 @default.
- W2065065847 cites W1981066233 @default.
- W2065065847 cites W1984007765 @default.
- W2065065847 cites W1984411147 @default.
- W2065065847 cites W1993311818 @default.
- W2065065847 cites W1993373375 @default.
- W2065065847 cites W1993504067 @default.
- W2065065847 cites W2000894800 @default.
- W2065065847 cites W2005120531 @default.
- W2065065847 cites W2006729360 @default.
- W2065065847 cites W2007239726 @default.
- W2065065847 cites W2010226025 @default.
- W2065065847 cites W2015749091 @default.
- W2065065847 cites W2017562442 @default.
- W2065065847 cites W2017581710 @default.
- W2065065847 cites W2018664696 @default.
- W2065065847 cites W2018891673 @default.
- W2065065847 cites W2019637120 @default.
- W2065065847 cites W2020758485 @default.
- W2065065847 cites W2022014262 @default.
- W2065065847 cites W2022305337 @default.
- W2065065847 cites W2022405655 @default.
- W2065065847 cites W2023599099 @default.
- W2065065847 cites W2023785357 @default.
- W2065065847 cites W2028208129 @default.
- W2065065847 cites W2029973808 @default.
- W2065065847 cites W2030496781 @default.
- W2065065847 cites W2032146145 @default.
- W2065065847 cites W2034616600 @default.
- W2065065847 cites W2035531193 @default.
- W2065065847 cites W2038187175 @default.
- W2065065847 cites W2041701381 @default.
- W2065065847 cites W2047445921 @default.
- W2065065847 cites W2051491642 @default.
- W2065065847 cites W2055509359 @default.
- W2065065847 cites W2059901024 @default.
- W2065065847 cites W2064117423 @default.
- W2065065847 cites W2067309949 @default.
- W2065065847 cites W2068500323 @default.
- W2065065847 cites W2070619601 @default.
- W2065065847 cites W2070769462 @default.
- W2065065847 cites W2071712061 @default.
- W2065065847 cites W2072441361 @default.
- W2065065847 cites W2075991090 @default.
- W2065065847 cites W2080763813 @default.
- W2065065847 cites W2081572333 @default.
- W2065065847 cites W2081924426 @default.
- W2065065847 cites W2083764992 @default.
- W2065065847 cites W2084919823 @default.
- W2065065847 cites W2090107650 @default.
- W2065065847 cites W2091026347 @default.
- W2065065847 cites W2097162294 @default.
- W2065065847 cites W2101099825 @default.
- W2065065847 cites W2110096168 @default.
- W2065065847 cites W2115123250 @default.
- W2065065847 cites W2121505579 @default.
- W2065065847 cites W2123009279 @default.
- W2065065847 cites W2125708747 @default.
- W2065065847 cites W2126941192 @default.
- W2065065847 cites W2127341873 @default.
- W2065065847 cites W2129852583 @default.
- W2065065847 cites W2130532181 @default.
- W2065065847 cites W2131009328 @default.
- W2065065847 cites W2142998520 @default.
- W2065065847 cites W2154884921 @default.
- W2065065847 cites W2162459979 @default.
- W2065065847 cites W2167905528 @default.
- W2065065847 doi "https://doi.org/10.1016/j.tox.2012.11.011" @default.
- W2065065847 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23219591" @default.
- W2065065847 hasPublicationYear "2013" @default.
- W2065065847 type Work @default.
- W2065065847 sameAs 2065065847 @default.
- W2065065847 citedByCount "58" @default.
- W2065065847 countsByYear W20650658472013 @default.
- W2065065847 countsByYear W20650658472014 @default.
- W2065065847 countsByYear W20650658472015 @default.
- W2065065847 countsByYear W20650658472016 @default.
- W2065065847 countsByYear W20650658472017 @default.
- W2065065847 countsByYear W20650658472018 @default.
- W2065065847 countsByYear W20650658472019 @default.