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- W2065076430 abstract "A mutant strain of E. coli (rap−) has been isolated which blocks the growth of phages λ, 434, and ∅80. Phage 424 and various non-lambdoid phages are not affected. λ mutants that can bypass the rap block are of two general types. First, a presumed point mutant mapping between h and att provides partial bypass of the block. Second, all deletions and substitutions that eliminate or substitute one or both recognition regions of the attachment site restore a high level of growth. However, a point mutation in the crossover region of the attachment site does not bypass the block, and the rap mutation does not affect Int-promoted λ recombination. While the mechanism by which rap blocks phage development is unknown, the block implies a new and potentially interesting form of phage-host interaction." @default.
- W2065076430 created "2016-06-24" @default.
- W2065076430 creator A5039004138 @default.
- W2065076430 creator A5078695242 @default.
- W2065076430 date "1976-06-01" @default.
- W2065076430 modified "2023-10-16" @default.
- W2065076430 title "A mutant of Escherichia coli that prevents growth of phage lambda and is bypassed by lambda mutants in a nonessential region of the genome" @default.
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- W2065076430 doi "https://doi.org/10.1016/0042-6822(76)90380-9" @default.
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