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• W2065076670 abstract "Abstract The low mechanical reliability of bioactive glasses (BGs) is a critical limitation in hard tissue prosthetics. Herein, the effect of sol–gel-derived calcium borosilicate system (CBS) with low-melting temperature on the mechanical properties and biodegradation of 45S5 BG-derived bioactive glass-ceramics (BGC) was investigated. The 45S5 BG-based BGCs with 0–20% CBS content were fabricated via sintering treatment at 700–1100 °C. The results confirmed that the sintering temperature range of 850–900 °C for the 10% CBS-containing BGC (45S5/CBS10) exhibited higher compressive strength than those treated at either lower or higher temperature, and the strength was almost 2.5–3.0-fold higher than that of the pure 45S5 BGC. The 45S5/CBS10 BGCs fabricated at 850–900 °C showed excellent biodegradation and bioactivity when soaking in Tris buffer and simulated body fluid, while the compressive strength only decreased slightly. Specifically, the 45S5/CBS10 scaffolds with a porosity of ~ 70% showed ~ 8.0 MPa in compressive strength, which is comparable to the compressive values of human trabecular bone. It is, therefore, believed that the sol–gel-derived CBS is suitable for reinforcing the melt-derived BG and is helpful for developing low-temperature sintering BGC porous biomaterials because of their integration in appreciable biodegradation and reasonable mechanical properties." @default.
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• W2065076670 date "2014-12-01" @default.
• W2065076670 modified "2023-10-11" @default.
• W2065076670 title "Effect of borosilicate glass on the mechanical and biodegradation properties of 45S5-derived bioactive glass-ceramics" @default.
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• W2065076670 doi "https://doi.org/10.1016/j.jnoncrysol.2014.09.002" @default.
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