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• W2065124257 abstract "Objectives: To evaluate the effect of gadoxetic acid enhancement on the detection and characterisation of focal hepatic lesions on T2 weighted and diffusion weighted (DW) images. Methods: A total of 63 consecutive patients underwent T2 weighted and DW imaging before and after gadoxetic acid enhancement. Two blinded readers independently identified all of the focal lesions using a five-point confidence scale and characterised each lesion using a three-point scale: 1, non-solid; 2, indeterminate; and 3, solid. For both T2 weighted and DW imaging, the accuracies for detecting focal lesions were compared using the free-response receiver operating characteristic analysis; the accuracies for lesion characterisation were compared using the McNemar test between non-enhanced and gadoxetic acid-enhanced image sets. For hepatic lesions ≥1 cm, the lesion-to-liver contrast-to-noise ratio (CNR) and the apparent diffusion coefficient (ADC) were compared in the non-enhanced and enhanced image sets using the generalised estimating equations. Results: For both T2 weighted and DW images, the accuracies for detecting focal lesions (p≥0.52) and those for lesion characterisation (p≥0.63) did not differ significantly between the non-enhanced and enhanced image sets. The lesion-to-liver CNR was significantly higher on enhanced DW images than on non-enhanced DW images (p=0.02), although the difference was not significant for T2 weighted imaging (p=0.65). The mean ADC values of lesions did not differ significantly on enhanced and non-enhanced DW imaging (p=0.75). Conclusion: The acquisition of T2 weighted and DW images after administration of gadoxetic acid has no significant effect on the detection or characterisation of focal hepatic lesions, although it improves the lesion-to-liver CNR on DW images." @default.
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• W2065124257 date "2012-01-01" @default.
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• W2065124257 title "The effect of gadoxetic acid enhancement on lesion detection and characterisation using<i>T</i>₂weighted imaging and diffusion weighted imaging of the liver" @default.
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• W2065124257 doi "https://doi.org/10.1259/bjr/12929687" @default.
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