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- W2065131497 abstract "With the increasing worldwide prevalence of diabetes the resulting complications, their consequences and treatment will lead to a greater social and financial burden on society. One of the many organs to be affected is bone. Loss of bone is observed in type 1 diabetes, in extreme cases mirroring osteoporosis, thus a greater risk of fracture. In the case of type 2 diabetes, both a loss and an increase of bone has been observed, although in both cases the quality of the bone overall was poorer, again leading to a greater risk of fracture. Once a fracture has occurred, healing is delayed in diabetes, including nonunion. The reasons leading to such changes in the state of the bone and fracture healing in diabetes is under investigation, including at the cellular and the molecular levels. In comparison with our knowledge of events in normal bone homeostasis and fracture healing, that for diabetes is much more limited, particularly in patients. However, progress is being made, especially with the use of animal models for both diabetes types. Identifying the molecular and cellular changes in the bone in diabetes and understanding how they arise will allow for targeted intervention to improve diabetic bone, thus helping to counter conditions such as Charcot foot as well as preventing fracture and accelerating healing when a fracture does occur." @default.
- W2065131497 created "2016-06-24" @default.
- W2065131497 creator A5034897442 @default.
- W2065131497 creator A5045752192 @default.
- W2065131497 creator A5082249674 @default.
- W2065131497 date "2011-03-01" @default.
- W2065131497 modified "2023-10-13" @default.
- W2065131497 title "Review: The Diabetic Bone: A Cellular and Molecular Perspective" @default.
- W2065131497 cites W1568578844 @default.
- W2065131497 cites W1575440037 @default.
- W2065131497 cites W1876762378 @default.
- W2065131497 cites W1964227409 @default.
- W2065131497 cites W1965853251 @default.
- W2065131497 cites W1966136179 @default.
- W2065131497 cites W1967125513 @default.
- W2065131497 cites W1968133605 @default.
- W2065131497 cites W1968677875 @default.
- W2065131497 cites W1969179229 @default.
- W2065131497 cites W1969568665 @default.
- W2065131497 cites W1971333176 @default.
- W2065131497 cites W1971589882 @default.
- W2065131497 cites W1976006601 @default.
- W2065131497 cites W1976718154 @default.
- W2065131497 cites W1977317101 @default.
- W2065131497 cites W1978934561 @default.
- W2065131497 cites W1979579950 @default.
- W2065131497 cites W1979821211 @default.
- W2065131497 cites W1981865349 @default.
- W2065131497 cites W1982043015 @default.
- W2065131497 cites W1982272373 @default.
- W2065131497 cites W1984979932 @default.
- W2065131497 cites W1985013075 @default.
- W2065131497 cites W1985260819 @default.
- W2065131497 cites W1985260952 @default.
- W2065131497 cites W1985416777 @default.
- W2065131497 cites W1985807246 @default.
- W2065131497 cites W1986213636 @default.
- W2065131497 cites W1988533223 @default.
- W2065131497 cites W1989034239 @default.
- W2065131497 cites W1990028531 @default.
- W2065131497 cites W1992215893 @default.
- W2065131497 cites W1992570938 @default.
- W2065131497 cites W1993160438 @default.
- W2065131497 cites W1993580279 @default.
- W2065131497 cites W1994291240 @default.
- W2065131497 cites W1994416294 @default.
- W2065131497 cites W1995084234 @default.
- W2065131497 cites W1995331546 @default.
- W2065131497 cites W1995407912 @default.
- W2065131497 cites W1995438729 @default.
- W2065131497 cites W1995715562 @default.
- W2065131497 cites W1995861797 @default.
- W2065131497 cites W2000521606 @default.
- W2065131497 cites W2000746306 @default.
- W2065131497 cites W2000970827 @default.
- W2065131497 cites W2003780860 @default.
- W2065131497 cites W2004004680 @default.
- W2065131497 cites W2005119833 @default.
- W2065131497 cites W2005491364 @default.
- W2065131497 cites W2006253826 @default.
- W2065131497 cites W2006345660 @default.
- W2065131497 cites W2006919588 @default.
- W2065131497 cites W2007555613 @default.
- W2065131497 cites W2007808887 @default.
- W2065131497 cites W2007901604 @default.
- W2065131497 cites W2009425929 @default.
- W2065131497 cites W2010455271 @default.
- W2065131497 cites W2010901408 @default.
- W2065131497 cites W2014692301 @default.
- W2065131497 cites W2015418035 @default.
- W2065131497 cites W2015496410 @default.
- W2065131497 cites W2017004213 @default.
- W2065131497 cites W2019287716 @default.
- W2065131497 cites W2019522259 @default.
- W2065131497 cites W2019706412 @default.
- W2065131497 cites W2020267609 @default.
- W2065131497 cites W2020480694 @default.
- W2065131497 cites W2021350370 @default.
- W2065131497 cites W2021465534 @default.
- W2065131497 cites W2023407069 @default.
- W2065131497 cites W2024416118 @default.
- W2065131497 cites W2027137772 @default.
- W2065131497 cites W2028682730 @default.
- W2065131497 cites W2029372953 @default.
- W2065131497 cites W2029662899 @default.
- W2065131497 cites W2030574557 @default.
- W2065131497 cites W2032107044 @default.
- W2065131497 cites W2032988230 @default.
- W2065131497 cites W2034138847 @default.
- W2065131497 cites W2034550065 @default.
- W2065131497 cites W2034578561 @default.
- W2065131497 cites W2035797927 @default.
- W2065131497 cites W2036256326 @default.
- W2065131497 cites W2036431532 @default.
- W2065131497 cites W2037333519 @default.
- W2065131497 cites W2040873162 @default.
- W2065131497 cites W2040908032 @default.
- W2065131497 cites W2041425125 @default.