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- W2065140405 endingPage "T126" @default.
- W2065140405 startingPage "T116" @default.
- W2065140405 abstract "Resection of a cerebral arteriovenous malformation (AVM), epileptic focus, or glioma, ideally has a prerequisite of microscopic delineation of the lesion borders in relation to the normal gray and white matter that mediate critical functions. Currently, Wada testing and functional magnetic resonance imaging (fMRI) are used for preoperative mapping of critical function, whereas electrical stimulation mapping (ESM) is used for intraoperative mapping. For lesion delineation, MRI and positron emission tomography (PET) are used preoperatively, whereas microscopy and histological sectioning are used intraoperatively. However, for lesions near eloquent cortex, these imaging techniques may lack sufficient resolution to define the relationship between the lesion and language function, and thus not accurately determine which patients will benefit from neurosurgical resection of the lesion without iatrogenic aphasia. Optical techniques such as intraoperative optical imaging of intrinsic signals (iOIS) show great promise for the precise functional mapping of cortices, as well as delineation of the borders of AVMs, epileptic foci, and gliomas. Here we first review the physiology of neuroimaging, and then progress towards the validation and justification of using intraoperative optical techniques, especially in relation to neurosurgical planning of resection AVMs, epileptic foci, and gliomas near or in eloquent cortex. We conclude with a short description of potential novel intraoperative optical techniques." @default.
- W2065140405 created "2016-06-24" @default.
- W2065140405 creator A5014949118 @default.
- W2065140405 creator A5019868064 @default.
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- W2065140405 creator A5072674557 @default.
- W2065140405 creator A5082661128 @default.
- W2065140405 creator A5091699765 @default.
- W2065140405 date "2009-08-01" @default.
- W2065140405 modified "2023-10-07" @default.
- W2065140405 title "Current trends in intraoperative optical imaging for functional brain mapping and delineation of lesions of language cortex" @default.
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