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• W2065142775 abstract "Twelve segments of ventral nerve cord (VNC) from donor earthworms, Eisenia foetida, were transplanted into recipient worms from which a comparable length of VNC had been removed. Within the first few days after transplantation, bud-like formations, containing outgrowths of the giant nerve fibers, were evident at the ends of transplanted and recipient VNC. Morphological and electrophysiological evidence indicated that by 4–10 days after transplantation, medial (MGF) and lateral (LGF) giant fibers within the transplanted VNC formed cell-specific connections with their counterparts in the recipient VNC. Although the diameters of the giant fiber connections in the transplant-recipient junctions were often larger than normal, spike conduction across the junction was initially slow (approximately 1.0 m/s) but gradually increased over the next 2–3 weeks. Within the transplant, giant fibers were initially normal in appearance, but spike conduction was slow (1–2 m/s). During the next few weeks velocities increased by as much as fourfold and then stabilized for the next several months. However, by 4–5 weeks after transplantation, giant fiber morphology within the transplant was altered significantly, as indicated by the formation of numerous branch-like extensions along the length of each giant fiber. By 9–10 months there were further morphological changes in the transplant, as indicated by decreased branching of the giant fibers and altered neuropile. Despite these morphological changes, through-conduction of giant fiber spikes remained reliable." @default.
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• W2065142775 date "1985-07-01" @default.
• W2065142775 modified "2023-09-27" @default.
• W2065142775 title "Donor-recipient interconnections between giant nerve fibers in transplanted ventral nerve cords of earthworms" @default.
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• W2065142775 doi "https://doi.org/10.1002/neu.480160404" @default.
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