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- W2065146585 abstract "Magnetic resonance imaging and water-suppressed proton magnetic resonance spectroscopic imaging were used to study N-acetylaspartate and other metabolites in a patient with severe hypoxic–ischemic encephalopathy. The N-acetylaspartate signal, a putative marker of neuronal density, was markedly reduced in the forebrain. The relative signal intensity of choline-containing metabolites, which are more abundant in astrocytes than neurons, was increased. These results support the hypothesis that water-suppressed proton magnetic resonance spectroscopic imaging measurements of N-acetylaspartate may be useful for noninvasive detection of selective neuronal loss in a variety of disease states in the human brain." @default.
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- W2065146585 date "1994-04-01" @default.
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- W2065146585 title "Magnetic resonance spectroscopy ofN-acetylaspartate in hypoxic-ischemic encephalopathy" @default.
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- W2065146585 doi "https://doi.org/10.1002/ana.410350420" @default.
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