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- W2065159105 abstract "Amino acid hydroxamate derivatives inhibit the recently characterized enkephalin-degrading aminopeptidase from human blood (α-aminoacyl-peptide hydrolase, EC 3.4.11.11). The efficiency of inhibition depends on the structure of the amino acid hydroxamate employed. Amino acid hydroxamate decivatives also inhibit metalloendopeptidases and enkephalin-degrading enzymes from rat brain. The degradation of enkephalin in blood and in the brain seems to be under the control of a number of metallopeptidases: suitable amino acid hydroxamate derivatives can therefore be proposed as general inhibitors of enkephalin breakdown." @default.
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- W2065159105 date "1982-07-01" @default.
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- W2065159105 title "Amino acid hydroxamates as inhibitors of the human enkephalin-degrading aminopeptidase" @default.
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- W2065159105 doi "https://doi.org/10.1016/0006-291x(82)91514-5" @default.
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