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- W2065202452 abstract "Abstract 1. The effects of serotonin, D-ala2met-enkephalinamide, GTP and several non-physiological modulators of adenylate cyclase were examined on cAMP system of the segmental ganglia of the leech Hirudo medicinalis. 2. Serotonin stimulated both cAMP levels and adenlate cylase, while the opiate slightly, but significantly, inhibited cAMP synthesis. 3. Adenylate cyclase activity was dually regulated by GTP, stimulated by GTPyS and Gpp(NH)p and inhibited by GDPβS. 4. Fluoride ions greatly enhanced the enzyme activity, while forskolin was ineffective on basal and serotonin-stimulated cAMP synthesis." @default.
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- W2065202452 date "1989-01-01" @default.
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- W2065202452 title "Some properties of adenylate cyclase in the segmental ganglia of the leech Hirudo medicinalis" @default.
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- W2065202452 doi "https://doi.org/10.1016/0742-8413(89)90125-4" @default.
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