FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065203786> ?p ?o ?g. }

• W2065203786 endingPage "222" @default.
• W2065203786 startingPage "213" @default.
• W2065203786 abstract "In this work, we provide novel insight into the morphology of dissecting abdominal aortic aneurysms in angiotensin II-infused mice. We demonstrate why they exhibit a large variation in shape and, unlike their human counterparts, are located suprarenally rather than infrarenally.We combined synchrotron-based, ultra-high resolution ex vivo imaging (phase contrast X-Ray tomographic microscopy) with in vivo imaging (high-frequency ultrasound and contrast-enhanced micro-CT) and image-guided histology. In all mice, we observed a tear in the tunica media of the abdominal aorta near the ostium of the celiac artery. Independently we found that, unlike the gradual luminal expansion typical for human aneurysms, the outer diameter increase of angiotensin II-induced dissecting aneurysms in mice was related to one or several intramural haematomas. These were caused by ruptures of the tunica media near the ostium of small suprarenal side branches, which had never been detected by the established small animal imaging techniques. The tear near the celiac artery led to apparent luminal dilatation, while the intramural haematoma led to a dissection of the tunica adventitia on the left suprarenal side of the aorta. The number of ruptured branches was higher in those aneurysms that extended into the thoracic aorta, which explained the observed variability in aneurysm shape.Our results are the first to describe apparent luminal dilatation, suprarenal branch ruptures, and intramural haematoma formation in dissecting abdominal aortic aneurysms in mice. Moreover, we validate and demonstrate the vast potential of phase contrast X-ray tomographic microscopy in cardiovascular small animal applications." @default.
• W2065203786 created "2016-06-24" @default.
• W2065203786 creator A5002647826 @default.
• W2065203786 creator A5022201491 @default.
• W2065203786 creator A5025470988 @default.
• W2065203786 creator A5026293552 @default.
• W2065203786 creator A5036171403 @default.
• W2065203786 creator A5036457394 @default.
• W2065203786 creator A5046762590 @default.
• W2065203786 creator A5061562246 @default.
• W2065203786 creator A5070667550 @default.
• W2065203786 creator A5077199077 @default.
• W2065203786 creator A5086558448 @default.
• W2065203786 date "2014-12-23" @default.
• W2065203786 modified "2023-09-30" @default.
• W2065203786 title "Dissecting abdominal aortic aneurysm in Ang II-infused mice: suprarenal branch ruptures and apparent luminal dilatation" @default.
• W2065203786 cites W1479894630 @default.
• W2065203786 cites W1892208898 @default.
• W2065203786 cites W1964693177 @default.
• W2065203786 cites W1966652592 @default.
• W2065203786 cites W1968790199 @default.
• W2065203786 cites W1968974963 @default.
• W2065203786 cites W1970518087 @default.
• W2065203786 cites W1996702326 @default.
• W2065203786 cites W2010234819 @default.
• W2065203786 cites W2012740979 @default.
• W2065203786 cites W2020790664 @default.
• W2065203786 cites W2038658250 @default.
• W2065203786 cites W2041923191 @default.
• W2065203786 cites W2041938961 @default.
• W2065203786 cites W2047942069 @default.
• W2065203786 cites W2055772387 @default.
• W2065203786 cites W2057082690 @default.
• W2065203786 cites W2060458030 @default.
• W2065203786 cites W2066270582 @default.
• W2065203786 cites W2066660579 @default.
• W2065203786 cites W2075653292 @default.
• W2065203786 cites W2080373577 @default.
• W2065203786 cites W2082062303 @default.
• W2065203786 cites W2083324974 @default.
• W2065203786 cites W2090013635 @default.
• W2065203786 cites W2096928208 @default.
• W2065203786 cites W2100272414 @default.
• W2065203786 cites W2107122524 @default.
• W2065203786 cites W2109329928 @default.
• W2065203786 cites W2111309096 @default.
• W2065203786 cites W2112389698 @default.
• W2065203786 cites W2132076028 @default.
• W2065203786 cites W2138041199 @default.
• W2065203786 cites W2138408681 @default.
• W2065203786 cites W2141814949 @default.
• W2065203786 cites W2156815041 @default.
• W2065203786 cites W2159351650 @default.
• W2065203786 cites W2164721838 @default.
• W2065203786 cites W2170649042 @default.
• W2065203786 doi "https://doi.org/10.1093/cvr/cvu257" @default.
• W2065203786 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25538157" @default.
• W2065203786 hasPublicationYear "2014" @default.
• W2065203786 type Work @default.
• W2065203786 sameAs 2065203786 @default.
• W2065203786 citedByCount "60" @default.
• W2065203786 countsByYear W20652037862015 @default.
• W2065203786 countsByYear W20652037862016 @default.
• W2065203786 countsByYear W20652037862017 @default.
• W2065203786 countsByYear W20652037862018 @default.
• W2065203786 countsByYear W20652037862019 @default.
• W2065203786 countsByYear W20652037862020 @default.
• W2065203786 countsByYear W20652037862021 @default.
• W2065203786 countsByYear W20652037862022 @default.
• W2065203786 countsByYear W20652037862023 @default.
• W2065203786 crossrefType "journal-article" @default.
• W2065203786 hasAuthorship W2065203786A5002647826 @default.
• W2065203786 hasAuthorship W2065203786A5022201491 @default.
• W2065203786 hasAuthorship W2065203786A5025470988 @default.
• W2065203786 hasAuthorship W2065203786A5026293552 @default.
• W2065203786 hasAuthorship W2065203786A5036171403 @default.
• W2065203786 hasAuthorship W2065203786A5036457394 @default.
• W2065203786 hasAuthorship W2065203786A5046762590 @default.
• W2065203786 hasAuthorship W2065203786A5061562246 @default.
• W2065203786 hasAuthorship W2065203786A5070667550 @default.
• W2065203786 hasAuthorship W2065203786A5077199077 @default.
• W2065203786 hasAuthorship W2065203786A5086558448 @default.
• W2065203786 hasBestOaLocation W20652037861 @default.
• W2065203786 hasConcept C105702510 @default.
• W2065203786 hasConcept C126322002 @default.
• W2065203786 hasConcept C126838900 @default.
• W2065203786 hasConcept C2775862295 @default.
• W2065203786 hasConcept C2776098176 @default.
• W2065203786 hasConcept C2776716733 @default.
• W2065203786 hasConcept C2777178098 @default.
• W2065203786 hasConcept C2777323849 @default.
• W2065203786 hasConcept C2778930955 @default.
• W2065203786 hasConcept C2779980429 @default.
• W2065203786 hasConcept C2780007028 @default.
• W2065203786 hasConcept C2780520971 @default.
• W2065203786 hasConcept C2987047532 @default.
• W2065203786 hasConcept C71924100 @default.
• W2065203786 hasConceptScore W2065203786C105702510 @default.

• next