Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065241376> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2065241376 endingPage "1029" @default.
- W2065241376 startingPage "1025" @default.
- W2065241376 abstract "The mortality of patients admitted to intensive care units with haematological malignancy is high. A humane approach to the management of the critically ill as well as efficient use of limited resources requires careful selection of those patients who are most likely to benefit from intensive care. To delineate more accurately the factors influencing outcome in these patients the records of 60 consecutive admissions to the intensive care unit (37 male, 23 female) with haematological malignancy were reviewed retrospectively. Fifty patients were in acute respiratory failure, most commonly (34 patients) with a combination of pneumonia and septicaemic shock. The severity of the acute illness was assessed by the APACHE II (acute physiology and chronic health evaluation II) score and number of organ systems affected. Thirteen patients survived to leave hospital. The mortality of patients with haematological malignancy was consistently higher than predicted from a large validation study of APACHE II in a mixed population of critically ill patients. Moreover, no patient with an APACHE II score of greater than 26 survived. Mortality among the 22 patients with relapsed malignancy (21 deaths), was significantly higher than among the 35 patients at first presentation (26 deaths). On discharge from the intensive care unit all survivors had responded well to chemotherapy and had normal or raised peripheral white cell counts. They included seven patients who had recovered from leucopenia (white cell count less than 0.5 X 10(9)/l). In contrast, 36 of the 47 patients who died were leucopenic at the time of death. The overall mortality of critically ill patients with haematological malignancy is higher than equivalently ill patients without cancer. The dysfunction of an increasing number of organ systems, an APACHE II score of greater than 30, failure of the malignancy to respond to chemotherapy, and persistent leucopenia all point to a poor outcome." @default.
- W2065241376 created "2016-06-24" @default.
- W2065241376 creator A5002249012 @default.
- W2065241376 creator A5013041636 @default.
- W2065241376 creator A5030407490 @default.
- W2065241376 creator A5048555023 @default.
- W2065241376 date "1988-04-09" @default.
- W2065241376 modified "2023-09-24" @default.
- W2065241376 title "Prognosis of patients receiving intensive care for lifethreatening medical complications of haematological malignancy" @default.
- W2065241376 cites W1991072987 @default.
- W2065241376 cites W2000046019 @default.
- W2065241376 cites W2001385153 @default.
- W2065241376 cites W2006211638 @default.
- W2065241376 cites W2021051359 @default.
- W2065241376 cites W2023023793 @default.
- W2065241376 cites W2024773667 @default.
- W2065241376 cites W2067832095 @default.
- W2065241376 cites W2093704084 @default.
- W2065241376 cites W2164971443 @default.
- W2065241376 cites W2411949624 @default.
- W2065241376 cites W2417244426 @default.
- W2065241376 cites W4293242440 @default.
- W2065241376 cites W4299536388 @default.
- W2065241376 cites W2107978811 @default.
- W2065241376 doi "https://doi.org/10.1136/bmj.296.6628.1025" @default.
- W2065241376 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2545556" @default.
- W2065241376 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3130123" @default.
- W2065241376 hasPublicationYear "1988" @default.
- W2065241376 type Work @default.
- W2065241376 sameAs 2065241376 @default.
- W2065241376 citedByCount "117" @default.
- W2065241376 countsByYear W20652413762012 @default.
- W2065241376 countsByYear W20652413762013 @default.
- W2065241376 countsByYear W20652413762014 @default.
- W2065241376 countsByYear W20652413762015 @default.
- W2065241376 countsByYear W20652413762016 @default.
- W2065241376 countsByYear W20652413762017 @default.
- W2065241376 countsByYear W20652413762018 @default.
- W2065241376 countsByYear W20652413762019 @default.
- W2065241376 countsByYear W20652413762020 @default.
- W2065241376 countsByYear W20652413762021 @default.
- W2065241376 countsByYear W20652413762022 @default.
- W2065241376 countsByYear W20652413762023 @default.
- W2065241376 crossrefType "journal-article" @default.
- W2065241376 hasAuthorship W2065241376A5002249012 @default.
- W2065241376 hasAuthorship W2065241376A5013041636 @default.
- W2065241376 hasAuthorship W2065241376A5030407490 @default.
- W2065241376 hasAuthorship W2065241376A5048555023 @default.
- W2065241376 hasBestOaLocation W20652413762 @default.
- W2065241376 hasConcept C126322002 @default.
- W2065241376 hasConcept C177713679 @default.
- W2065241376 hasConcept C195910791 @default.
- W2065241376 hasConcept C2776376669 @default.
- W2065241376 hasConcept C2777628635 @default.
- W2065241376 hasConcept C2777914695 @default.
- W2065241376 hasConcept C2778384902 @default.
- W2065241376 hasConcept C2779399171 @default.
- W2065241376 hasConcept C2780347030 @default.
- W2065241376 hasConcept C2908647359 @default.
- W2065241376 hasConcept C2987404301 @default.
- W2065241376 hasConcept C71924100 @default.
- W2065241376 hasConcept C99454951 @default.
- W2065241376 hasConceptScore W2065241376C126322002 @default.
- W2065241376 hasConceptScore W2065241376C177713679 @default.
- W2065241376 hasConceptScore W2065241376C195910791 @default.
- W2065241376 hasConceptScore W2065241376C2776376669 @default.
- W2065241376 hasConceptScore W2065241376C2777628635 @default.
- W2065241376 hasConceptScore W2065241376C2777914695 @default.
- W2065241376 hasConceptScore W2065241376C2778384902 @default.
- W2065241376 hasConceptScore W2065241376C2779399171 @default.
- W2065241376 hasConceptScore W2065241376C2780347030 @default.
- W2065241376 hasConceptScore W2065241376C2908647359 @default.
- W2065241376 hasConceptScore W2065241376C2987404301 @default.
- W2065241376 hasConceptScore W2065241376C71924100 @default.
- W2065241376 hasConceptScore W2065241376C99454951 @default.
- W2065241376 hasIssue "6628" @default.
- W2065241376 hasLocation W20652413761 @default.
- W2065241376 hasLocation W20652413762 @default.
- W2065241376 hasLocation W20652413763 @default.
- W2065241376 hasLocation W20652413764 @default.
- W2065241376 hasOpenAccess W2065241376 @default.
- W2065241376 hasPrimaryLocation W20652413761 @default.
- W2065241376 hasRelatedWork W162778554 @default.
- W2065241376 hasRelatedWork W1973511833 @default.
- W2065241376 hasRelatedWork W2076678520 @default.
- W2065241376 hasRelatedWork W2272068335 @default.
- W2065241376 hasRelatedWork W2411292388 @default.
- W2065241376 hasRelatedWork W2412376098 @default.
- W2065241376 hasRelatedWork W2415186040 @default.
- W2065241376 hasRelatedWork W2791919475 @default.
- W2065241376 hasRelatedWork W2977556239 @default.
- W2065241376 hasRelatedWork W3202006358 @default.
- W2065241376 hasVolume "296" @default.
- W2065241376 isParatext "false" @default.
- W2065241376 isRetracted "false" @default.
- W2065241376 magId "2065241376" @default.
- W2065241376 workType "article" @default.