FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065267118> ?p ?o ?g. }

• W2065267118 endingPage "2572" @default.
• W2065267118 startingPage "2566" @default.
• W2065267118 abstract "Multiple brain morphometric changes have been reported in late-life depression (LLD), mostly in studies comparing volumes of circumscribed brain areas. The aim of our study is to characterize the volumetric changes of multiple gray matter regions in relation to age of onset/duration of illness. We predicted that the association of gray matter volumes with total duration of illness and age of onset would differ depending on whether the region was susceptible to the toxic effects of chronic exposure to cortisol or to the vascular/neurodegenerative changes accompanying prodromal dementia. Seventy-one elderly depressed subjects were studied along with thirty-two comparison subjects. High-resolution T1-weighted brain MRIs were processed using an automated labeling pathway technique. To protect against type-I error, we combined the right and left hemisphere volume data. We sampled 24 regions of interest (ROIs). We used the primary visual cortex volume to normalize for individual variations in brain size. LLD Subjects had smaller volumes than non-depressed subjects in 17 of the 24 examined ROIs. Shorter duration of illness and later age of onset was correlated with smaller volumes of parahippocampal area and parietal inferior area. A later age of onset was also correlated with smaller volumes of several frontal and temporal areas, cingulum, and putamen. Our findings support a dementia prodrome model more strongly than a toxic stress model in this group of subjects. However, it remains likely that both processes as well as other factors contribute to the heterogeneity of volumetric brain changes in LLD." @default.
• W2065267118 created "2016-06-24" @default.
• W2065267118 creator A5027958721 @default.
• W2065267118 creator A5064264687 @default.
• W2065267118 creator A5064979886 @default.
• W2065267118 creator A5066006962 @default.
• W2065267118 creator A5081107493 @default.
• W2065267118 creator A5085696063 @default.
• W2065267118 creator A5088728325 @default.
• W2065267118 creator A5091438181 @default.
• W2065267118 date "2007-12-12" @default.
• W2065267118 modified "2023-10-17" @default.
• W2065267118 title "Gray Matter Changes in Late Life Depression—a Structural MRI Analysis" @default.
• W2065267118 cites W1642124290 @default.
• W2065267118 cites W1847168837 @default.
• W2065267118 cites W1964929451 @default.
• W2065267118 cites W1965138864 @default.
• W2065267118 cites W1977238326 @default.
• W2065267118 cites W1982277568 @default.
• W2065267118 cites W1983536668 @default.
• W2065267118 cites W1985199195 @default.
• W2065267118 cites W1987528796 @default.
• W2065267118 cites W1992144433 @default.
• W2065267118 cites W1998530261 @default.
• W2065267118 cites W2002050752 @default.
• W2065267118 cites W2003191738 @default.
• W2065267118 cites W2019316537 @default.
• W2065267118 cites W2025644609 @default.
• W2065267118 cites W2041514266 @default.
• W2065267118 cites W2044710410 @default.
• W2065267118 cites W2048534868 @default.
• W2065267118 cites W2048738245 @default.
• W2065267118 cites W2053133374 @default.
• W2065267118 cites W2058046532 @default.
• W2065267118 cites W2064397126 @default.
• W2065267118 cites W2071881327 @default.
• W2065267118 cites W2073531245 @default.
• W2065267118 cites W2075104388 @default.
• W2065267118 cites W2095032469 @default.
• W2065267118 cites W2101800098 @default.
• W2065267118 cites W2103069600 @default.
• W2065267118 cites W2113590396 @default.
• W2065267118 cites W2114092300 @default.
• W2065267118 cites W2114613490 @default.
• W2065267118 cites W2120499016 @default.
• W2065267118 cites W2121358117 @default.
• W2065267118 cites W2121878996 @default.
• W2065267118 cites W2137114476 @default.
• W2065267118 cites W2167123432 @default.
• W2065267118 cites W2172277297 @default.
• W2065267118 cites W66834283 @default.
• W2065267118 cites W68901995 @default.
• W2065267118 doi "https://doi.org/10.1038/sj.npp.1301655" @default.
• W2065267118 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2872084" @default.
• W2065267118 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18075490" @default.
• W2065267118 hasPublicationYear "2007" @default.
• W2065267118 type Work @default.
• W2065267118 sameAs 2065267118 @default.
• W2065267118 citedByCount "126" @default.
• W2065267118 countsByYear W20652671182012 @default.
• W2065267118 countsByYear W20652671182013 @default.
• W2065267118 countsByYear W20652671182014 @default.
• W2065267118 countsByYear W20652671182015 @default.
• W2065267118 countsByYear W20652671182016 @default.
• W2065267118 countsByYear W20652671182017 @default.
• W2065267118 countsByYear W20652671182018 @default.
• W2065267118 countsByYear W20652671182019 @default.
• W2065267118 countsByYear W20652671182020 @default.
• W2065267118 countsByYear W20652671182021 @default.
• W2065267118 countsByYear W20652671182022 @default.
• W2065267118 countsByYear W20652671182023 @default.
• W2065267118 crossrefType "journal-article" @default.
• W2065267118 hasAuthorship W2065267118A5027958721 @default.
• W2065267118 hasAuthorship W2065267118A5064264687 @default.
• W2065267118 hasAuthorship W2065267118A5064979886 @default.
• W2065267118 hasAuthorship W2065267118A5066006962 @default.
• W2065267118 hasAuthorship W2065267118A5081107493 @default.
• W2065267118 hasAuthorship W2065267118A5085696063 @default.
• W2065267118 hasAuthorship W2065267118A5088728325 @default.
• W2065267118 hasAuthorship W2065267118A5091438181 @default.
• W2065267118 hasBestOaLocation W20652671181 @default.
• W2065267118 hasConcept C118552586 @default.
• W2065267118 hasConcept C126322002 @default.
• W2065267118 hasConcept C126838900 @default.
• W2065267118 hasConcept C143409427 @default.
• W2065267118 hasConcept C148762608 @default.
• W2065267118 hasConcept C15744967 @default.
• W2065267118 hasConcept C169760540 @default.
• W2065267118 hasConcept C2777193593 @default.
• W2065267118 hasConcept C2778013878 @default.
• W2065267118 hasConcept C2779134260 @default.
• W2065267118 hasConcept C2779483572 @default.
• W2065267118 hasConcept C2779714222 @default.
• W2065267118 hasConcept C2779727114 @default.
• W2065267118 hasConcept C2780292510 @default.
• W2065267118 hasConcept C2781192897 @default.
• W2065267118 hasConcept C2781357127 @default.
• W2065267118 hasConcept C65835030 @default.

• next