Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065296872> ?p ?o ?g. }
- W2065296872 abstract "Efforts have been focused on developing in vitro assays for the study of microvessels because in vivo animal studies are more time-consuming, expensive, and observation and quantification are very challenging. However, conventional in vitro microvessel assays have limitations when representing in vivo microvessels with respect to three-dimensional (3D) geometry and providing continuous fluid flow. Using a combination of photolithographic reflowable photoresist technique, soft lithography, and microfluidics, we have developed a multi-depth circular cross-sectional endothelialized microchannels-on-a-chip, which mimics the 3D geometry of in vivo microvessels and runs under controlled continuous perfusion flow. A positive reflowable photoresist was used to fabricate a master mold with a semicircular cross-sectional microchannel network. By the alignment and bonding of the two polydimethylsiloxane (PDMS) microchannels replicated from the master mold, a cylindrical microchannel network was created. The diameters of the microchannels can be well controlled. In addition, primary human umbilical vein endothelial cells (HUVECs) seeded inside the chip showed that the cells lined the inner surface of the microchannels under controlled perfusion lasting for a time period between 4 days to 2 weeks." @default.
- W2065296872 created "2016-06-24" @default.
- W2065296872 creator A5003079948 @default.
- W2065296872 creator A5009232538 @default.
- W2065296872 creator A5042830817 @default.
- W2065296872 creator A5063146180 @default.
- W2065296872 date "2013-10-21" @default.
- W2065296872 modified "2023-09-27" @default.
- W2065296872 title "Procedure for the Development of Multi-depth Circular Cross-sectional Endothelialized Microchannels-on-a-chip" @default.
- W2065296872 cites W100681333 @default.
- W2065296872 cites W1489547988 @default.
- W2065296872 cites W1516603921 @default.
- W2065296872 cites W1544053957 @default.
- W2065296872 cites W1551620887 @default.
- W2065296872 cites W1561655396 @default.
- W2065296872 cites W1562397511 @default.
- W2065296872 cites W1635443418 @default.
- W2065296872 cites W1687956552 @default.
- W2065296872 cites W181233549 @default.
- W2065296872 cites W1897582447 @default.
- W2065296872 cites W1949173079 @default.
- W2065296872 cites W1968553256 @default.
- W2065296872 cites W1970606334 @default.
- W2065296872 cites W1971054825 @default.
- W2065296872 cites W1976412820 @default.
- W2065296872 cites W1980275250 @default.
- W2065296872 cites W1982748428 @default.
- W2065296872 cites W1985280243 @default.
- W2065296872 cites W1988524161 @default.
- W2065296872 cites W2002265285 @default.
- W2065296872 cites W2003986773 @default.
- W2065296872 cites W2006383118 @default.
- W2065296872 cites W2006385054 @default.
- W2065296872 cites W2012397669 @default.
- W2065296872 cites W2014180858 @default.
- W2065296872 cites W2036827054 @default.
- W2065296872 cites W2043938126 @default.
- W2065296872 cites W2059661208 @default.
- W2065296872 cites W2059672779 @default.
- W2065296872 cites W2059852491 @default.
- W2065296872 cites W2063665585 @default.
- W2065296872 cites W2065062834 @default.
- W2065296872 cites W2066711736 @default.
- W2065296872 cites W2072389844 @default.
- W2065296872 cites W2077125839 @default.
- W2065296872 cites W2082322317 @default.
- W2065296872 cites W2091904117 @default.
- W2065296872 cites W2114308816 @default.
- W2065296872 cites W2118530605 @default.
- W2065296872 cites W2120895512 @default.
- W2065296872 cites W2129574021 @default.
- W2065296872 cites W2129611593 @default.
- W2065296872 cites W2134135049 @default.
- W2065296872 cites W2134257943 @default.
- W2065296872 cites W2139237590 @default.
- W2065296872 cites W2155788949 @default.
- W2065296872 cites W2157544852 @default.
- W2065296872 cites W2242679990 @default.
- W2065296872 cites W2412143783 @default.
- W2065296872 cites W655127611 @default.
- W2065296872 cites W2063632365 @default.
- W2065296872 doi "https://doi.org/10.3791/50771" @default.
- W2065296872 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3947964" @default.
- W2065296872 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24193102" @default.
- W2065296872 hasPublicationYear "2013" @default.
- W2065296872 type Work @default.
- W2065296872 sameAs 2065296872 @default.
- W2065296872 citedByCount "1" @default.
- W2065296872 countsByYear W20652968722021 @default.
- W2065296872 crossrefType "journal-article" @default.
- W2065296872 hasAuthorship W2065296872A5003079948 @default.
- W2065296872 hasAuthorship W2065296872A5009232538 @default.
- W2065296872 hasAuthorship W2065296872A5042830817 @default.
- W2065296872 hasAuthorship W2065296872A5063146180 @default.
- W2065296872 hasBestOaLocation W20652968722 @default.
- W2065296872 hasConcept C118524077 @default.
- W2065296872 hasConcept C119599485 @default.
- W2065296872 hasConcept C127413603 @default.
- W2065296872 hasConcept C132651336 @default.
- W2065296872 hasConcept C134406635 @default.
- W2065296872 hasConcept C136229726 @default.
- W2065296872 hasConcept C136525101 @default.
- W2065296872 hasConcept C142724271 @default.
- W2065296872 hasConcept C146978453 @default.
- W2065296872 hasConcept C150903083 @default.
- W2065296872 hasConcept C165005293 @default.
- W2065296872 hasConcept C171250308 @default.
- W2065296872 hasConcept C185592680 @default.
- W2065296872 hasConcept C192562407 @default.
- W2065296872 hasConcept C202751555 @default.
- W2065296872 hasConcept C204787440 @default.
- W2065296872 hasConcept C207001950 @default.
- W2065296872 hasConcept C2777411675 @default.
- W2065296872 hasConcept C2779227376 @default.
- W2065296872 hasConcept C2779849746 @default.
- W2065296872 hasConcept C55493867 @default.
- W2065296872 hasConcept C63662833 @default.
- W2065296872 hasConcept C71924100 @default.
- W2065296872 hasConcept C8673954 @default.
- W2065296872 hasConcept C86803240 @default.