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• W2065304148 abstract "Abstract Six patients subjected to renal homotransplantation and simultaneous bilateral nephrectomy have been studied to characterize the diuresis observed after transplant and to seek evidence of specific tubular functions in the period immediately after transplantation. A diuresis of 5,825 to 14,855 ml. per 24 hours, lasting less than 72 hours was observed in five of six cases. The magnitude of the diuresis was found to relate directly to initial creatinine clearance. Investigation of urinary composition revealed the diuresis to be osmotic. The ratio of electrolyte osmolal clearance to osmolal clearance exceeded 50 per cent in five of the six patients. Urinary urea constituted a significant but lesser portion of urinary solute. In five of six cases, mean creatinine clearances 6 and 18 hours after the transplant were 65.4 and 66.5 ml. a minute, respectively. The mean para-aminohippurate (PAH) clearance was 247 ml. a minute at 6 hours and 358 ml. a minute at 18 hours in the four patients studied at both times. Activity of specific tubular mechanisms for glucose, sodium and solute-free water reabsorption and for potassium secretion was demonstrated in the first five days following renal homotransplantation." @default.
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• W2065304148 date "1965-06-01" @default.
• W2065304148 modified "2023-09-23" @default.
• W2065304148 title "Function of the renal homograft in man immediately after transplantation" @default.
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• W2065304148 doi "https://doi.org/10.1016/0002-9343(65)90006-9" @default.
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