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- W2065350056 abstract "Currently accepted modalities of treatment for atherosclerotic coronary artery disease (CAD) include pharmacological therapy, and revascularization with either bypass surgery or percutaneous coronary intervention (PCI). Similarly, conventional treatment of congestive heart failure (HF) is limited to medical therapy, temporary assist devices and in a select few, cardiac transplantation. A significant subset of patients with severe symptomatic CAD and end stage HF is not eligible for these traditional methods of treatment. In spite of maximal medical and revascularization therapy, these patients may not get adequate symptomatic relief. After a decade of investigations, gene therapy is emerging as a promising therapeutic option for this group of patients. This review discusses myocardial angiogenesis as a therapeutic modality in these patients including therapeutic angiogenesis with growth factors and cell transplantation. (Mol Cell Biochem 264: 157–167, 2004)" @default.
- W2065350056 created "2016-06-24" @default.
- W2065350056 creator A5002582638 @default.
- W2065350056 date "2004-09-01" @default.
- W2065350056 modified "2023-10-14" @default.
- W2065350056 title "Current clinical perspectives on myocardial angiogenesis" @default.
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- W2065350056 doi "https://doi.org/10.1023/b:mcbi.0000044385.55012.8f" @default.
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