Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065352309> ?p ?o ?g. }
- W2065352309 endingPage "734" @default.
- W2065352309 startingPage "729" @default.
- W2065352309 abstract "The Y2 subtype of neuropeptide tyrosine (NPY) receptors (Y2R) and some neuropeptides have been studied with in situ hybridization in sensory and autonomic neurons of rat and monkey. Between 10% and 20% of the lumbar dorsal root ganglion (DRG) neuron profiles (NPs) contain Y2R mRNA in the rat and monkey. In rat DRGs Y2R mRNA is expressed in calcitonin gene-related peptide (CGRP)-positive, medium-sized, and large neurons, that is in a complementary fashion to the Y1R that is located in small CGRP neurons. In monkey DRGs Y2R mRNA is expressed mainly in small neurons. Peripheral axotomy up-regulates the Y2R in small and large DRG neurons in both species. Y2R and NPY mRNAs are colocalized in many large neurons in axotomized rat DRGs. Y2R mRNA is expressed in 50% of the NPs in the nodose ganglion with a modest increase after axotomy. Y2R mRNA is detected in a few NPs in normal rat superior cervical ganglia, with a marked increase after transection of the carotid nerves. No Y2R mRNA-positive, but many (≈30%) weakly Y1R mRNA-positive NPs were found in the sphenopalatine ganglion. Finally, Y2R mRNA levels increase in rat spinal motoneurons after axotomy. Thus, under normal circumstances NPY may act on Y1 and Y2Rs expressed, respectively, in small and large CGRP-positive DRG neurons in the rat. Y2R may be an important receptor in the viscero-sensory neurons. Y2Rs may be particularly important after axotomy serving as presynaptic and/or autoreceptors on rat DRG, superior cervical ganglion, and nodose ganglion neurons and as presynaptic receptors in monkey DRG neurons." @default.
- W2065352309 created "2016-06-24" @default.
- W2065352309 creator A5015046435 @default.
- W2065352309 creator A5027446790 @default.
- W2065352309 creator A5037991850 @default.
- W2065352309 creator A5043880888 @default.
- W2065352309 creator A5046146318 @default.
- W2065352309 creator A5073568638 @default.
- W2065352309 creator A5077494149 @default.
- W2065352309 creator A5077555809 @default.
- W2065352309 date "1997-01-21" @default.
- W2065352309 modified "2023-10-18" @default.
- W2065352309 title "Expression and regulation of the neuropeptide Y Y2 receptor in sensory and autonomic ganglia" @default.
- W2065352309 cites W1502386136 @default.
- W2065352309 cites W1627689726 @default.
- W2065352309 cites W1964395662 @default.
- W2065352309 cites W1974781356 @default.
- W2065352309 cites W1979316334 @default.
- W2065352309 cites W1980435560 @default.
- W2065352309 cites W1984214402 @default.
- W2065352309 cites W1987039829 @default.
- W2065352309 cites W1987863605 @default.
- W2065352309 cites W1988628530 @default.
- W2065352309 cites W1992719775 @default.
- W2065352309 cites W1996942493 @default.
- W2065352309 cites W2003982930 @default.
- W2065352309 cites W2015301110 @default.
- W2065352309 cites W2020681325 @default.
- W2065352309 cites W2022168313 @default.
- W2065352309 cites W2031513088 @default.
- W2065352309 cites W2034997180 @default.
- W2065352309 cites W2043026787 @default.
- W2065352309 cites W2049582606 @default.
- W2065352309 cites W2052173587 @default.
- W2065352309 cites W2053726057 @default.
- W2065352309 cites W2053807193 @default.
- W2065352309 cites W2054954302 @default.
- W2065352309 cites W2065526595 @default.
- W2065352309 cites W2079201209 @default.
- W2065352309 cites W2086727023 @default.
- W2065352309 cites W2087056848 @default.
- W2065352309 cites W2089658653 @default.
- W2065352309 cites W2128780500 @default.
- W2065352309 cites W2131681649 @default.
- W2065352309 cites W2140099199 @default.
- W2065352309 cites W2144715110 @default.
- W2065352309 cites W2163143518 @default.
- W2065352309 cites W2223896132 @default.
- W2065352309 cites W2406605290 @default.
- W2065352309 doi "https://doi.org/10.1073/pnas.94.2.729" @default.
- W2065352309 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/19582" @default.
- W2065352309 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9012853" @default.
- W2065352309 hasPublicationYear "1997" @default.
- W2065352309 type Work @default.
- W2065352309 sameAs 2065352309 @default.
- W2065352309 citedByCount "112" @default.
- W2065352309 countsByYear W20653523092012 @default.
- W2065352309 countsByYear W20653523092014 @default.
- W2065352309 countsByYear W20653523092015 @default.
- W2065352309 countsByYear W20653523092017 @default.
- W2065352309 countsByYear W20653523092018 @default.
- W2065352309 countsByYear W20653523092019 @default.
- W2065352309 countsByYear W20653523092021 @default.
- W2065352309 countsByYear W20653523092022 @default.
- W2065352309 crossrefType "journal-article" @default.
- W2065352309 hasAuthorship W2065352309A5015046435 @default.
- W2065352309 hasAuthorship W2065352309A5027446790 @default.
- W2065352309 hasAuthorship W2065352309A5037991850 @default.
- W2065352309 hasAuthorship W2065352309A5043880888 @default.
- W2065352309 hasAuthorship W2065352309A5046146318 @default.
- W2065352309 hasAuthorship W2065352309A5073568638 @default.
- W2065352309 hasAuthorship W2065352309A5077494149 @default.
- W2065352309 hasAuthorship W2065352309A5077555809 @default.
- W2065352309 hasBestOaLocation W20653523092 @default.
- W2065352309 hasConcept C105702510 @default.
- W2065352309 hasConcept C118303440 @default.
- W2065352309 hasConcept C126322002 @default.
- W2065352309 hasConcept C134018914 @default.
- W2065352309 hasConcept C163170386 @default.
- W2065352309 hasConcept C170493617 @default.
- W2065352309 hasConcept C24998067 @default.
- W2065352309 hasConcept C2778993773 @default.
- W2065352309 hasConcept C2779683492 @default.
- W2065352309 hasConcept C2781334511 @default.
- W2065352309 hasConcept C2781404750 @default.
- W2065352309 hasConcept C2909127448 @default.
- W2065352309 hasConcept C2910476448 @default.
- W2065352309 hasConcept C529278444 @default.
- W2065352309 hasConcept C71924100 @default.
- W2065352309 hasConcept C86803240 @default.
- W2065352309 hasConcept C93984277 @default.
- W2065352309 hasConceptScore W2065352309C105702510 @default.
- W2065352309 hasConceptScore W2065352309C118303440 @default.
- W2065352309 hasConceptScore W2065352309C126322002 @default.
- W2065352309 hasConceptScore W2065352309C134018914 @default.
- W2065352309 hasConceptScore W2065352309C163170386 @default.
- W2065352309 hasConceptScore W2065352309C170493617 @default.
- W2065352309 hasConceptScore W2065352309C24998067 @default.